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The effect of iron on mammalian cortical neurons in culture.

作者信息

Swaiman K F, Machen V L

出版信息

Neurochem Res. 1985 Sep;10(9):1261-8. doi: 10.1007/BF00964844.

DOI:10.1007/BF00964844
PMID:4058658
Abstract

We added iron in the ferric form to predominantly neuronal, cortical cell cultures, and determined clonazepam-displaceable [3H]diazepam binding, choline acetyltransferase activity, high-affinity [3H]GABA uptake, and glutamic acid decarboxylase activity. Chronic exposure (14 days) to low concentrations (0.01, 0.04, and 0.1 micrograms/ml) of added ferric iron resulted in a significant decrease in each of the measures studied.

摘要

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本文引用的文献

1
DETERMINATION OF SERUM IRON USING SULFONATED DIPHENYLPHENANTHROLINE.使用磺化二苯基菲啰啉测定血清铁
Am J Med Technol. 1964 Mar-Apr;30:71-80.
2
Alzheimer's disease; a clinico-pathologic analysis of twenty-three cases with a theory on pathogenesis.阿尔茨海默病;23例临床病理分析及发病机制理论
J Nerv Ment Dis. 1953 Aug;118(2):97-130.
3
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Brain Res. 1980 May 19;190(1):123-38. doi: 10.1016/0006-8993(80)91164-6.
Neurochem Res. 1986 Sep;11(9):1241-8. doi: 10.1007/BF00966119.
4
Levels and sub-cellular distribution of physiologically important metal ions in neuronal cells cultured from chick embryo cerebral cortex.鸡胚大脑皮层培养神经元细胞中生理重要金属离子的水平及亚细胞分布
Neurochem Res. 1988 Dec;13(12):1163-7. doi: 10.1007/BF00971634.
5
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Neurochem Res. 1989 Jul;14(7):683-8. doi: 10.1007/BF00964879.
6
Iron-induced lipid peroxidation and inhibition of dopamine synthesis in striatum synaptosomes.铁诱导的纹状体突触体脂质过氧化及多巴胺合成抑制。
Neurochem Res. 1989 Jul;14(7):597-605. doi: 10.1007/BF00964867.
7
Effect of ferric nitrilotriacetate on predominantly cortical glial cell cultures.
Neurochem Res. 1990 May;15(5):501-5. doi: 10.1007/BF00966207.
8
Effect of ferric nitrilotriacetate on rostral mesencephalic cells.次氮基三乙酸铁对中脑嘴侧细胞的作用。
Neurochem Res. 1991 Dec;16(12):1269-74. doi: 10.1007/BF00966657.
4
Transferrin uptake by cultured rat embryo fibroblasts. The influence of temperature and incubation time, subcellular distribution and short-term kinetic studies.培养的大鼠胚胎成纤维细胞对转铁蛋白的摄取。温度和孵育时间的影响、亚细胞分布及短期动力学研究
Eur J Biochem. 1981 Apr;115(3):611-8.
5
Cellular proliferation and susceptibility to iron toxicity in iron loaded cell cultures.
Scand J Haematol. 1982 Mar;28(3):227-32. doi: 10.1111/j.1600-0609.1982.tb00519.x.
6
Glutamate decarboxylase immunoreactivity and gamma-[3H] aminobutyric acid accumulation within the same neurons in dissociated cell cultures of cerebral cortex.大脑皮质解离细胞培养物中同一神经元内谷氨酸脱羧酶免疫反应性及γ-[³H]氨基丁酸积聚
J Neurosci. 1983 Feb;3(2):376-82. doi: 10.1523/JNEUROSCI.03-02-00376.1983.
7
Sea-blue histiocytes, lymphocytic cytosomes, movement disorder and 59Fe-uptake in basal ganglia: Hallervorden-Spatz disease or ceroid storage disease with abnormal isotope scan?
Neurology. 1983 Mar;33(3):301-5. doi: 10.1212/wnl.33.3.301.
8
Phenylalanine and phenylacetate adversely affect developing mammalian brain neurons.苯丙氨酸和苯乙酸对发育中的哺乳动物脑神经元有不利影响。
Neurology. 1984 Sep;34(9):1246-50. doi: 10.1212/wnl.34.9.1246.
9
Iron uptake by mammalian cortical neurons.哺乳动物皮层神经元对铁的摄取。
Ann Neurol. 1984 Jul;16(1):66-70. doi: 10.1002/ana.410160113.
10
An in situ assay for determination of benzodiazepine binding.一种用于测定苯二氮䓬结合的原位测定法。
Dev Neurosci. 1982 Mar-Jun;5(2-3):271-7. doi: 10.1159/000112685.