细胞疗法可使神经-胶质-血管单元恢复活力。 - Suppr

Suppr

超能文献

Cell therapy rejuvenates the neuro-glial-vascular unit.

作者信息

Chen Bandy

机构信息

Department of Medicine, UC San Diego School of Medicine, La Jolla, CA, USA.

出版信息

Neural Regen Res. 2026 Apr 1;21(4):1542-1543. doi: 10.4103/NRR.NRR-D-24-01359. Epub 2025 Jan 29.

DOI:10.4103/NRR.NRR-D-24-01359

PMID:40587238

Abstract

摘要

相似文献

Cell therapy rejuvenates the neuro-glial-vascular unit.细胞疗法可使神经-胶质-血管单元恢复活力。

Neural Regen Res. 2026 Apr 1;21(4):1542-1543. doi: 10.4103/NRR.NRR-D-24-01359. Epub 2025 Jan 29.

Dynamic Neuro-Glial-Vascular Responses in a Mouse Model of Vascular Cognitive Impairment.血管性认知障碍小鼠模型中的动态神经-胶质-血管反应

Neuroglia. 2024 Dec;5(4):505-521. doi: 10.3390/neuroglia5040032. Epub 2024 Dec 19.

Glial Cell-Based Vascular Mechanisms and Transplantation Therapies in Brain Vessel and Neurodegenerative Diseases.基于胶质细胞的血管机制及在脑血管和神经退行性疾病中的移植疗法

Front Cell Neurosci. 2021 Mar 26;15:627682. doi: 10.3389/fncel.2021.627682. eCollection 2021.

Mapping Connectome in Mammalian Brain: A Novel Approach by Bioengineering Neuro-Glia specific Vectors.绘制哺乳动物大脑连接组：一种通过生物工程神经胶质特异性载体的新方法。

J Theor Biol. 2020 Jul 7;496:110244. doi: 10.1016/j.jtbi.2020.110244. Epub 2020 Apr 20.

The "Neuro-Glial-Vascular" Unit: The Role of Glia in Neurovascular Unit Formation and Dysfunction.“神经-胶质-血管”单元：胶质细胞在神经血管单元形成和功能障碍中的作用

Front Cell Dev Biol. 2021 Sep 27;9:732820. doi: 10.3389/fcell.2021.732820. eCollection 2021.

Bioenergetic Impairment in the Neuro-Glia-Vascular Unit: An Emerging Physiopathology during Aging.神经-胶质-血管单元中的生物能量损伤：衰老过程中一种新出现的病理生理学现象。

Aging Dis. 2021 Dec 1;12(8):2080-2095. doi: 10.14336/AD.2021.04017. eCollection 2021 Dec.

Neuro-glial differentiation of human bone marrow stem cells in vitro.人骨髓干细胞的体外神经胶质分化

Exp Neurol. 2005 Jun;193(2):312-25. doi: 10.1016/j.expneurol.2004.12.013.

Pharmacological inhibition of Na/K-ATPase induces neurovascular degeneration and glial cell alteration in the rat retina.钠钾-ATP 酶的药理学抑制会导致大鼠视网膜的神经血管退化和神经胶质细胞改变。

Exp Eye Res. 2022 Jul;220:109107. doi: 10.1016/j.exer.2022.109107. Epub 2022 May 11.

The interrelations between malfunctioning DNA damage response (DDR) and the functionality of the neuro-glio-vascular unit.DNA 损伤反应（DDR）故障与神经胶质血管单元功能之间的相互关系。

DNA Repair (Amst). 2013 Aug;12(8):543-57. doi: 10.1016/j.dnarep.2013.04.007. Epub 2013 May 23.

Acute effects of systemic inflammation upon the neuro-glial-vascular unit and cerebrovascular function.全身炎症对神经-胶质-血管单元及脑血管功能的急性影响。

Brain Behav Immun Health. 2020 May;5:100074. doi: 10.1016/j.bbih.2020.100074.

引用本文的文献

Blood‑brain barrier dysfunction in epilepsy: Mechanisms, therapeutic strategies and future orientation (Review).癫痫中的血脑屏障功能障碍：机制、治疗策略及未来方向（综述）

Int J Mol Med. 2025 Sep;56(3). doi: 10.3892/ijmm.2025.5577. Epub 2025 Jul 4.

本文引用的文献

CRISPR-edited human ES-derived oligodendrocyte progenitor cells improve remyelination in rodents.经 CRISPR 编辑的人胚胎干细胞源性少突胶质前体细胞可改善啮齿动物的髓鞘再生。

Nat Commun. 2024 Oct 9;15(1):8570. doi: 10.1038/s41467-024-52444-w.

Mesenchymal stem cells reduce long-term cognitive deficits and attenuate myelin disintegration and microglia activation following repetitive traumatic brain injury.间充质干细胞可减轻重复创伤性脑损伤后的长期认知缺陷，并减轻脱髓鞘和小胶质细胞激活。

Sci Prog. 2024 Jan-Mar;107(1):368504241231154. doi: 10.1177/00368504241231154.

Bone marrow-derived mononuclear cells ameliorate neurological function in chronic cerebral infarction model mice via improvement of cerebral blood flow.骨髓源单核细胞通过改善脑血流改善慢性脑梗死模型小鼠的神经功能。

Cytotherapy. 2023 Nov;25(11):1186-1199. doi: 10.1016/j.jcyt.2023.07.003. Epub 2023 Aug 8.

Co-transplantation of autologous T cells in a cell therapy for Parkinson's disease.自体 T 细胞共移植治疗帕金森病的细胞疗法。

Nature. 2023 Jul;619(7970):606-615. doi: 10.1038/s41586-023-06300-4. Epub 2023 Jul 12.

Generation of Periventricular Reactive Astrocytes Overexpressing Aquaporin 4 Is Stimulated by Mesenchymal Stem Cell Therapy.间质干细胞治疗可刺激室管膜下区反应性星形胶质细胞过表达水通道蛋白 4。

Int J Mol Sci. 2023 Mar 15;24(6):5640. doi: 10.3390/ijms24065640.

Overexpression of vascular endothelial growth factor enhances the neuroprotective effects of bone marrow mesenchymal stem cell transplantation in ischemic stroke.血管内皮生长因子的过表达增强了骨髓间充质干细胞移植对缺血性中风的神经保护作用。

Neural Regen Res. 2023 Jun;18(6):1286-1292. doi: 10.4103/1673-5374.358609.

Mesenchymal Stem Cells Improve Cognitive Impairment and Reduce Aβ Deposition Promoting AQP4 Polarity and Relieving Neuroinflammation in Rats With Chronic Hypertension-Induced Cerebral Small-Vessel Disease.间充质干细胞改善慢性高血压诱导的脑小血管病大鼠的认知障碍并减少β淀粉样蛋白沉积，促进水通道蛋白4极性并减轻神经炎症

Front Aging Neurosci. 2022 May 19;14:883503. doi: 10.3389/fnagi.2022.883503. eCollection 2022.

A combined cell and gene therapy approach for homotopic reconstruction of midbrain dopamine pathways using human pluripotent stem cells.一种使用人类多能干细胞对中脑多巴胺通路进行同位重建的细胞与基因联合治疗方法。

Cell Stem Cell. 2022 Mar 3;29(3):434-448.e5. doi: 10.1016/j.stem.2022.01.013. Epub 2022 Feb 17.

Combinatorial intranasal delivery of bone marrow mesenchymal stem cells and insulin-like growth factor-1 improves neurovascularization and functional outcomes following focal cerebral ischemia in mice.组合式鼻腔内递送骨髓间充质干细胞和胰岛素样生长因子-1 可改善小鼠局灶性脑缺血后的神经血管生成和功能预后。

Exp Neurol. 2021 Mar;337:113542. doi: 10.1016/j.expneurol.2020.113542. Epub 2020 Dec 1.

Human Stem Cell-Derived Neurons Repair Circuits and Restore Neural Function.人源干细胞衍生神经元修复回路并恢复神经功能。

Cell Stem Cell. 2021 Jan 7;28(1):112-126.e6. doi: 10.1016/j.stem.2020.08.014. Epub 2020 Sep 22.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验