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Cell therapy rejuvenates the neuro-glial-vascular unit.

作者信息

Chen Bandy

机构信息

Department of Medicine, UC San Diego School of Medicine, La Jolla, CA, USA.

出版信息

Neural Regen Res. 2026 Apr 1;21(4):1542-1543. doi: 10.4103/NRR.NRR-D-24-01359. Epub 2025 Jan 29.

DOI:10.4103/NRR.NRR-D-24-01359
PMID:40587238
Abstract
摘要

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Nat Commun. 2024 Oct 9;15(1):8570. doi: 10.1038/s41467-024-52444-w.
2
Mesenchymal stem cells reduce long-term cognitive deficits and attenuate myelin disintegration and microglia activation following repetitive traumatic brain injury.间充质干细胞可减轻重复创伤性脑损伤后的长期认知缺陷,并减轻脱髓鞘和小胶质细胞激活。
Sci Prog. 2024 Jan-Mar;107(1):368504241231154. doi: 10.1177/00368504241231154.
3
Bone marrow-derived mononuclear cells ameliorate neurological function in chronic cerebral infarction model mice via improvement of cerebral blood flow.
骨髓源单核细胞通过改善脑血流改善慢性脑梗死模型小鼠的神经功能。
Cytotherapy. 2023 Nov;25(11):1186-1199. doi: 10.1016/j.jcyt.2023.07.003. Epub 2023 Aug 8.
4
Co-transplantation of autologous T cells in a cell therapy for Parkinson's disease.自体 T 细胞共移植治疗帕金森病的细胞疗法。
Nature. 2023 Jul;619(7970):606-615. doi: 10.1038/s41586-023-06300-4. Epub 2023 Jul 12.
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Generation of Periventricular Reactive Astrocytes Overexpressing Aquaporin 4 Is Stimulated by Mesenchymal Stem Cell Therapy.间质干细胞治疗可刺激室管膜下区反应性星形胶质细胞过表达水通道蛋白 4。
Int J Mol Sci. 2023 Mar 15;24(6):5640. doi: 10.3390/ijms24065640.
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Overexpression of vascular endothelial growth factor enhances the neuroprotective effects of bone marrow mesenchymal stem cell transplantation in ischemic stroke.血管内皮生长因子的过表达增强了骨髓间充质干细胞移植对缺血性中风的神经保护作用。
Neural Regen Res. 2023 Jun;18(6):1286-1292. doi: 10.4103/1673-5374.358609.
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Mesenchymal Stem Cells Improve Cognitive Impairment and Reduce Aβ Deposition Promoting AQP4 Polarity and Relieving Neuroinflammation in Rats With Chronic Hypertension-Induced Cerebral Small-Vessel Disease.间充质干细胞改善慢性高血压诱导的脑小血管病大鼠的认知障碍并减少β淀粉样蛋白沉积,促进水通道蛋白4极性并减轻神经炎症
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