Zhang Huji, Wu Hongyan, Chen Zhongjiao, Zeng Bangfeng, Wang Long
Department of Pathology, Guiqian International General Hospital, Guiyang, Guizhou Province, China.
Guizhou Medical University, Guiyang, Guizhou Province, China.
Medicine (Baltimore). 2025 Jun 27;104(26):e43032. doi: 10.1097/MD.0000000000043032.
Glomus tumors (GTs) are painful and typically benign neoplasms found in the subungual region of the fingertips. However, the occurrence of multiple GT within nerve fascicles in the scapular region is rare.
A 41-year-old male presented with a 5-year history of progressive tenderness in the scapular region, accompanied by elevated local skin temperature. Magnetic resonance imaging revealed a small abnormal signal measuring approximately 3.1 × 3.0 mm, appearing hypoechoic on T1 and hyperechoic on T2 images, with clear boundaries. The lesion was initially diagnosed as an inflammatory lesion.
Multiple intraneural GT located within different nerve fascicles were diagnosed based on immunohistochemical analysis and hematoxylin-eosin staining.
The nodules were completely excised.
One week later, the patient reported significant pain relief compared with preoperative symptoms.
To the best of our knowledge, this is the first documented case of multiple intraneural GTs occurring within 3 different nerve fascicles to highlight the importance of accurate diagnosis to prevent misdiagnosis.
血管球瘤(GTs)是一种疼痛性且通常为良性的肿瘤,常见于指尖的甲下区域。然而,肩胛区域神经束内出现多发血管球瘤的情况较为罕见。
一名41岁男性,肩胛区域渐进性压痛5年,伴有局部皮肤温度升高。磁共振成像显示一个约3.1×3.0毫米的小异常信号,在T1图像上呈低回声,在T2图像上呈高回声,边界清晰。该病变最初被诊断为炎性病变。
基于免疫组织化学分析和苏木精-伊红染色,诊断为不同神经束内多发神经内血管球瘤。
结节被完全切除。
一周后,患者报告与术前症状相比疼痛明显缓解。
据我们所知,这是首例记录在案的在3个不同神经束内发生多发神经内血管球瘤的病例,强调了准确诊断以防止误诊的重要性。