Yagci Tarik, Aktas Selma, Turan Burcu, Gülec Bade, Altiner Halil I, Cinar Edanur
Department of Otorhinolaryngology Head and Neck Surgery, Bilecik Şeyh Edebali University Faculty of Medicine.
Department of Pulmonary Diseases.
J Craniofac Surg. 2025 Jun 30. doi: 10.1097/SCS.0000000000011626.
Obstructive Sleep Apnea Syndrome (OSAS) is a common sleep disorder characterized by respiratory arrests and is thought to affect vestibular system functions. In recent years, the Masseter VEMP test has become an alternative method for evaluating vestibular functions. This study aimed to assess the vestibular system through an mVEMP test in OSAS patients and determine the effects of the disease on vestibular functions.
This prospective study included 36 patients (72 ears) and 36 healthy controls (72 ears) diagnosed with OSAS. All participants underwent the mVEMP test to evaluate the functions of the vestibular system. N1 latency, P1 latency, P1-N1 difference, mean EMG activity, and amplitude values were assessed.
N1 latency was significantly longer in the OSAS group compared with the control group (P=0.013). P1 latency and the P1-N1 difference did not differ significantly between the groups (P=0.273 and 0.098, respectively). The mean EMG activity was significantly lower in the OSAS group compared with the control group (P=0.010). Amplitude was significantly higher in the OSAS group compared with the control group (P=0.024). Significant differences were observed in N1 and EMG values between the groups based on the severity of OSAS.
In this study, significant changes were observed in N1 latency, EMG activity, and amplitude during vestibular evaluation with mVEMP in patients with severe OSAS. It was noted that vestibular responses (N1 and EMG values) were more impacted in the severe OSAS group.
阻塞性睡眠呼吸暂停综合征（OSAS）是一种以呼吸暂停为特征的常见睡眠障碍，被认为会影响前庭系统功能。近年来，咬肌前庭诱发肌源性电位（mVEMP）测试已成为评估前庭功能的一种替代方法。本研究旨在通过对OSAS患者进行mVEMP测试来评估前庭系统，并确定该疾病对前庭功能的影响。
这项前瞻性研究纳入了36例（72耳）被诊断为OSAS的患者和36名健康对照者（72耳）。所有参与者均接受mVEMP测试以评估前庭系统功能。评估了N1潜伏期、P1潜伏期、P1 - N1差值、平均肌电图活动和幅值。
与对照组相比，OSAS组的N1潜伏期显著延长（P = 0.013）。两组之间的P1潜伏期和P1 - N1差值无显著差异（分别为P = 0.273和0.098）。与对照组相比，OSAS组的平均肌电图活动显著降低（P = 0.010）。与对照组相比，OSAS组的幅值显著更高（P = 0.024）。根据OSAS的严重程度，两组之间在N1和肌电图值方面观察到显著差异。
在本研究中，重度OSAS患者在前庭评估中通过mVEMP测试观察到N1潜伏期、肌电图活动和幅值有显著变化。值得注意的是，重度OSAS组的前庭反应（N1和肌电图值）受到的影响更大。
