Li Kun, Zhang Zhibin, Ran Jiangyu, Ma Liang, Meng Xiangyu
Graduate School of Xinjiang Medical University, Urumqi, China.
Minimally Invasive Spine Surgery, Sixth Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Front Surg. 2025 Jun 16;12:1585783. doi: 10.3389/fsurg.2025.1585783. eCollection 2025.
Lumbar spinal stenosis (LSS), the most frequently occurring degenerative spinal disease, significantly affects patient well-being. Preliminary clinical studies indicate favorable outcomes from unilateral biportal endoscopy (UBE) and unilateral endoscopy (UE) for managing LSS. This meta-analysis assessed the clinical effectiveness and safety profiles of unilateral laminotomy for bilateral decompression (ULBD) via these two minimally invasive endoscopic methods, aiming to establish evidence-based clinical recommendations.
A thorough examination of electronic databases was performed, encompassing PubMed, Cochrane Library, Web of Science, Embase, Medline, CNKI, WanFang, and VIP. Research assessing the clinical outcomes and complications of UBE-ULBD compared to UE-ULBD in the treatment of LSS was deemed suitable for inclusion. The outcome measures extracted comprised the Visual Analogue Scale (VAS), Oswestry Disability Index (ODI), duration of surgery, length of hospitalization, intraoperative blood loss, area of postoperative dural sac expansion, angle of ipsilateral facet joint resection, and occurrences of surgical complications.
Seventeen articles met inclusion criteria, encompassing one prospective cohort study, two case-control studies, and fourteen retrospective studies, involving 1, 457 total patients. The meta-analysis indicated that there were no statistically significant differences observed between the UBE and UE groups in terms of postoperative VAS scores for back and leg pain, as well as ODI scores at the intervals of 1 week, 3-6 months, and 6-12 months ( > 0.05). Nevertheless, the UBE methodology exhibited markedly reduced operative durations ( = 0.005) and enhanced postoperative expansion of the dural sac ( < 0.0001). Estimated intraoperative blood loss, hospitalization duration, complication rates, and ipsilateral facet joint resection angles were comparable between groups ( > 0.05).
The meta-analysis indicates that the UBE technique exhibits similar long-term clinical efficacy, blood loss, duration of hospital stay, and rates of complications when compared to the UE technique. However, the UBE group exhibited shorter surgical duration and greater dural sac expansion area.
腰椎管狭窄症(LSS)是最常见的退行性脊柱疾病,严重影响患者的生活质量。初步临床研究表明,单侧双通道内镜检查(UBE)和单通道内镜检查(UE)治疗LSS效果良好。本荟萃分析评估了通过这两种微创内镜方法进行单侧椎板切开双侧减压(ULBD)的临床有效性和安全性,旨在建立循证临床建议。
全面检索电子数据库,包括PubMed、Cochrane图书馆、Web of Science、Embase、Medline、中国知网、万方数据库和维普数据库。评估UBE-ULBD与UE-ULBD治疗LSS的临床结局和并发症的研究被认为适合纳入。提取的结局指标包括视觉模拟量表(VAS)、Oswestry功能障碍指数(ODI)、手术时长、住院时间、术中出血量、术后硬膜囊扩张面积、同侧小关节切除角度以及手术并发症的发生率。
17篇文章符合纳入标准,包括1项前瞻性队列研究、2项病例对照研究和14项回顾性研究,共涉及1457例患者。荟萃分析表明,UBE组和UE组在术后背部和腿部疼痛的VAS评分以及术后1周、3 - 6个月和6 - 12个月的ODI评分方面,差异无统计学意义(>0.05)。然而,UBE方法的手术时长显著缩短(=0.005),术后硬膜囊扩张明显增加(<0.0001)。两组间估计的术中出血量、住院时间、并发症发生率和同侧小关节切除角度相当(>0.05)。
荟萃分析表明,与UE技术相比,UBE技术在长期临床疗效、出血量、住院时间和并发症发生率方面相似。然而,UBE组的手术时间更短,硬膜囊扩张面积更大。