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卡纳塔克邦沿海地区第一家皮肤库:我们迄今为止的历程。

First Skin Bank of Coastal Karnataka: Our Journey so Far.

作者信息

Pereira C B, Thomas J, Pillai S C

机构信息

Department of Plastic Surgery, Kasturba Medical College, Manipal, India.

出版信息

Ann Burns Fire Disasters. 2025 Jun 30;38(2):100-107. eCollection 2025 Jun.

PMID:40589710
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12186152/
Abstract

In India around 7 million people suffer from burn injuries each year, with 140,000 deaths and 240,000 people having some form of residual disability. Human skin allograft is the gold standard for the treatment of burn wounds, hence having an in-house skin bank at a Burn Unit would be ideal. This article presents the efforts to introduce the concept of skin donation after death to the population of Udupi and Mangalore District, the response to this venture, and how our in-house skin bank helps in the management of patients in our burns centre. This study is a descriptive study done at our skin bank at Kasturba Medical College Hospital Manipal. All donor and recipient records of cadaveric allografts from MAHE Skin Bank from inception on 21-8-2021 to date were analysed. From inauguration to date, a total of 23 skin donation calls have been attended and a total of 56,560 sq. cm of skin harvested, with an average of 2570 sq. cm of skin harvested from the back and the bilateral lower limbs. A total of 20 inpatients in our burns unit received 28,475 sq. cm of cadaveric skin from our skin bank, with 3 patients dying due to sepsis (mortality rate - 15.00%). It is feasible to create a skin bank in a community with no concept of cadaveric skin donation, as demonstrated by the successful establishment of Coastal Karnataka's first skin bank at KMC Manipal Hospital.

摘要

在印度,每年约有700万人遭受烧伤,其中14万人死亡,24万人有某种形式的残疾。人同种异体皮肤移植是治疗烧伤创面的金标准,因此在烧伤科设立内部皮肤库是理想的。本文介绍了向乌度皮和芒格洛尔地区民众介绍死后皮肤捐赠概念的努力、对该项目的回应,以及我们的内部皮肤库如何帮助我们烧伤中心管理患者。本研究是在马尼帕尔卡斯图尔巴医学院医院的皮肤库进行的描述性研究。分析了从2021年8月21日成立至今MAHE皮肤库尸体同种异体移植的所有供体和受体记录。从开业至今,共接听了23次皮肤捐赠电话,共采集皮肤56560平方厘米,平均从背部和双侧下肢采集皮肤2570平方厘米。我们烧伤科共有20名住院患者接受了来自我们皮肤库的28475平方厘米尸体皮肤,其中3名患者因败血症死亡(死亡率-15.00%)。正如在马尼帕尔医院成功建立卡纳塔克邦沿海地区第一个皮肤库所证明的那样,在一个没有尸体皮肤捐赠概念的社区建立皮肤库是可行的。

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本文引用的文献

1
Skin banking at a regional burns centre-The way forward.地区烧伤中心的皮肤库——前进之路。
Burns. 2018 Jun;44(4):870-876. doi: 10.1016/j.burns.2017.11.010. Epub 2018 Apr 13.
2
Creation of Nepal's First Skin Bank: Challenges and Outcomes.尼泊尔首个皮肤库的创建:挑战与成果
Plast Reconstr Surg Glob Open. 2017 Nov 7;5(11):e1510. doi: 10.1097/GOX.0000000000001510. eCollection 2017 Nov.
3
Deceased donor skin allograft banking: Response and utilization.已故捐赠者皮肤同种异体移植库:反应与利用。
Indian J Plast Surg. 2010 Sep;43(Suppl):S114-20. doi: 10.4103/0970-0358.70732.
4
Euro Skin Bank: large scale skin-banking in Europe based on glycerol-preservation of donor skin.
Burns. 1994;20 Suppl 1:S4-9. doi: 10.1016/0305-4179(94)90080-9.