Gore Madhuri A, De Anuradha S
Department of Surgery, Lokmanya Tilak Municipal Medical College and General Hospital, Sion, Mumbai - 400 022, India.
Indian J Plast Surg. 2010 Sep;43(Suppl):S114-20. doi: 10.4103/0970-0358.70732.
In the absence of xenograft and biosynthetic skin substitutes, deceased donor skin allografts is a feasible option for saving life of patient with extensive burn injury in our country.
The first deceased donor skin allograft bank in India became functional at Lokmanya Tilak Municipal (LTM) medical college and hospital on 24(th) April 2000. The response of Indian society to this new concept of skin donation after death and the pattern of utilization of banked allografts from 2000 to 2010 has been presented in this study.
This allograft skin bank was established by the department of surgery. The departments of surgery and microbiology share the responsibility of smooth functioning of the bank.
The response in terms of number of donations and the profile of donors was analyzed from records. Pattern and outcome of allograft utilization was studied from specially designed forms.
During these ten years, 262 deceased donor skin allograft donations were received. The response showed significant improvement after counselling was extended to the community. Majority of the donors were above 70 years of age and procurement was done at home for most. Skin allografts from 249 donors were used for 165 patients in ten years. The outcome was encouraging with seven deaths in 151 recipients with burn injuries.
Our experience shows that the Indian society is ready to accept the concept of skin donation after death. Use of skin allografts is life saving for large burns. We need to prepare guidelines for the establishment of more skin banks in the country.
在缺乏异种移植和生物合成皮肤替代品的情况下，已故供体皮肤同种异体移植是挽救我国大面积烧伤患者生命的可行选择。
印度首个已故供体皮肤同种异体移植库于2000年4月24日在Lokmanya Tilak市立（LTM）医学院和医院开始运作。本研究展示了印度社会对死后皮肤捐赠这一新概念的反应以及2000年至2010年储存的同种异体移植的使用模式。
这个同种异体移植皮肤库由外科部门建立。外科和微生物学部门共同负责该库的顺利运作。
从记录中分析捐赠数量和捐赠者资料方面的反应。通过专门设计的表格研究同种异体移植的使用模式和结果。
在这十年间，共收到262例已故供体皮肤同种异体移植捐赠。在向社区推广咨询后，反应有了显著改善。大多数捐赠者年龄在70岁以上，大多数是在家中进行获取。十年间，来自249名捐赠者的皮肤同种异体移植用于165名患者。结果令人鼓舞，151名烧伤患者中有7人死亡。
我们的经验表明，印度社会愿意接受死后皮肤捐赠的概念。使用皮肤同种异体移植对大面积烧伤患者有救命作用。我们需要制定在该国建立更多皮肤库的指导方针。
