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Epigenetics Through Generations and Across Phylogenies: An Interview with Dr. Bluma Lesch.

作者信息

Abu-Shamma Reem, Marijic Buljubasic Andriana

机构信息

Department of Genetics, Yale School of Medicine, New Haven, CT, USA.

Yale School of Public Health, New Haven, CT, USA.

出版信息

Yale J Biol Med. 2025 Jun 30;98(2):253-256. doi: 10.59249/IIUD8470. eCollection 2025 Jun.

DOI:10.59249/IIUD8470
PMID:40589932
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12204026/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f225/12204026/f001ef64352e/yjbm_98_2_253_g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f225/12204026/b7b36a092064/yjbm_98_2_253_g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f225/12204026/f001ef64352e/yjbm_98_2_253_g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f225/12204026/b7b36a092064/yjbm_98_2_253_g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f225/12204026/f001ef64352e/yjbm_98_2_253_g02.jpg

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本文引用的文献

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Decoding the Epigenetics of Infertility: Mechanisms, Environmental Influences, and Therapeutic Strategies.解读不孕症的表观遗传学：机制、环境影响及治疗策略
Epigenomes. 2024 Sep 5;8(3):34. doi: 10.3390/epigenomes8030034.
2
Molecular mechanisms of transgenerational epigenetic inheritance.跨代表观遗传遗传的分子机制。
Nat Rev Genet. 2022 Jun;23(6):325-341. doi: 10.1038/s41576-021-00438-5. Epub 2022 Jan 4.
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Intergenerational epigenetic inheritance of cancer susceptibility in mammals.哺乳动物中癌症易感性的跨代表观遗传遗传。
Elife. 2019 Apr 9;8:e39380. doi: 10.7554/eLife.39380.
4
BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis.BCG 可教育造血干细胞产生针对结核病的保护性先天免疫。
Cell. 2018 Jan 11;172(1-2):176-190.e19. doi: 10.1016/j.cell.2017.12.031.
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Transgenerational response to stress in plants and its application for breeding.植物对胁迫的跨代反应及其在育种中的应用。
J Exp Bot. 2016 Mar;67(7):2081-92. doi: 10.1093/jxb/erw066. Epub 2016 Mar 3.
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Tumor necrosis factor receptor- associated factor 6 (TRAF6) regulation of development, function, and homeostasis of the immune system.肿瘤坏死因子受体相关因子6（TRAF6）对免疫系统发育、功能及稳态的调控
Immunol Rev. 2015 Jul;266(1):72-92. doi: 10.1111/imr.12302.
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Transgenerational inheritance of an acquired small RNA-based antiviral response in C. elegans.线虫中获得性小 RNA 抗病毒反应的跨代遗传
Cell. 2011 Dec 9;147(6):1248-56. doi: 10.1016/j.cell.2011.10.042. Epub 2011 Nov 23.
8
Origins, evolution, and phenotypic impact of new genes.新基因的起源、进化和表型影响。
Genome Res. 2010 Oct;20(10):1313-26. doi: 10.1101/gr.101386.109. Epub 2010 Jul 22.
9
Epigenetic programming by maternal behavior.母性行为的表观遗传编程。
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