He Jun, Gong Chen, Zhu Xiang, Zhu Shizhe, Geng Ayan, Kan Chaojie, Xu Sheng, Wang Tong, Guo Chuan, Zhu Lan, Wang Qinglei
Department of Rehabilitation Medicine, Changzhou Dean Hospital, Changzhou, China.
Department of Rehabilitation Medicine, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Front Neurol. 2025 Jun 16;16:1521687. doi: 10.3389/fneur.2025.1521687. eCollection 2025.
To explore the effects of postural control and cognition interference on cortical activation during balance tasks in stroke patients.
fNIRS was used to measure cortical activation in the SMC, PMC, and PFC in 30 subjects with supratentorial stroke while performing a postural single task (PST), cognitive single task (CST), and postural-cognitive dual task (DT). Differences in activation and correlations with patient balance or cognitive performance were analyzed.
CST induced a higher level of activation in the unaffected SMC and bilateral PMC compared to PST. While DT resulted in more activation of the bilateral SMC and bilateral PMC compared to PST. No difference was found between DT and CST. Correlation analysis showed that activation of ROIs during balance tasks showed a positive correlation with the balance ability and cognitive performance of subjects.
Both postural control and cognitive interference led to cortical activation changes during the tasks. Cognitive load was more likely to elicit greater cortical activation and approach the activation ceiling. These activations were intimately related to the patient's ability to balance and cognitive performance. Subjects with better balance have a greater reserve of resources to allocate, enabling them to cope with tasks and improve task performance.
ClinicalTrials.gov. Identifier ChiCTR2300077916.
探讨姿势控制和认知干扰对脑卒中患者平衡任务期间皮质激活的影响。
采用功能近红外光谱技术（fNIRS）测量30例幕上脑卒中患者在执行姿势单任务（PST）、认知单任务（CST）和姿势-认知双任务（DT）时，初级运动皮质（SMC）、辅助运动区（PMC）和前额叶皮质（PFC）的皮质激活情况。分析激活差异以及与患者平衡或认知表现的相关性。
与PST相比，CST在未受影响的SMC和双侧PMC中诱导出更高水平的激活。而与PST相比，DT导致双侧SMC和双侧PMC有更多激活。DT和CST之间未发现差异。相关性分析表明，平衡任务期间感兴趣区域（ROIs）的激活与受试者的平衡能力和认知表现呈正相关。
姿势控制和认知干扰在任务期间均导致皮质激活变化。认知负荷更有可能引发更大的皮质激活并接近激活上限。这些激活与患者的平衡能力和认知表现密切相关。平衡能力较好的受试者有更大的资源储备可供分配，使他们能够应对任务并提高任务表现。
ClinicalTrials.gov。标识符ChiCTR2300077916。
