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窄砧吻合器对右侧活体供肾肾切除术移植静脉长度的影响

Impact of Narrow Anvil Stapler on Graft Vein Length in Right-sided Living-donor Nephrectomy.

作者信息

Noguchi Hiroshi, Sato Yu, Hisadome Yu, Kubo Shinsuke, Kaku Keizo, Nakafusa Yuki, Miura Yoshifumi, Nakamura Masafumi

机构信息

Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Department of Surgery, Miyazaki Prefectural Miyazaki Hospital, Miyazaki, Japan.

出版信息

Transplant Direct. 2025 Jun 27;11(7):e1837. doi: 10.1097/TXD.0000000000001837. eCollection 2025 Jul.

Abstract

BACKGROUND

Right-sided living donor nephrectomy presents a challenge because of the shorter renal vein length, which may complicate vascular anastomosis during transplantation. We hypothesized that the use of a narrow anvil stapler could optimize vein preservation by allowing safer and more effective transection closer to the inferior vena cava. This study aimed to compare the effectiveness of the Signia Small Diameter Reload Short with Curved Tip (SDR) and the Tri-Staple 2.0 Reload (TSR) in preserving renal vein length and to evaluate their impact on donor and recipient outcomes.

METHODS

We conducted a retrospective observational cohort study of 39 right-sided donor nephrectomies performed at 2 institutions between May 2019 and December 2024. Patients were divided into 2 groups based on the stapler used: TSR (n = 16) and SDR (n = 23). Inverse probability of treatment weighting was applied to adjust for baseline differences, resulting in a final analysis of 11 TSR and 23 SDR cases. We evaluated renal vein length and overall surgical outcomes.

RESULTS

The SDR group had significantly longer renal vein lengths than the TSR group (23.0 ± 4.0 versus 17.5 ± 3.9 mm,  < 0.001). However, there were no significant differences in operative time, estimated blood loss, or perioperative complications in both donors and recipients. Warm ischemia time, rewarming time, and total ischemia time were also comparable between groups. Early postoperative serum creatinine levels did not differ significantly between recipient groups.

CONCLUSIONS

The SDR stapler provided a significant technical advantage in preserving renal vein length in right-sided donor nephrectomy. However, this did not translate into improved recipient outcomes, suggesting that surgical precision and vascular adaptation play a more critical role in transplantation success than vein length alone. Nonetheless, the ability to preserve greater vein length remains a potential advantage, particularly in challenging cases.

摘要

背景

由于右侧活体供肾肾切除术的肾静脉长度较短,这可能会使移植过程中的血管吻合复杂化,因此该手术具有挑战性。我们推测,使用窄砧吻合器可以通过在更靠近下腔静脉处进行更安全、更有效的横断来优化静脉保留。本研究旨在比较Signia小直径再装填短弯头(SDR)和三联吻合器2.0再装填(TSR)在保留肾静脉长度方面的有效性,并评估它们对供体和受体结局的影响。

方法

我们对2019年5月至2024年12月期间在2家机构进行的39例右侧供肾肾切除术进行了一项回顾性观察队列研究。根据所使用的吻合器将患者分为2组:TSR组(n = 16)和SDR组(n = 23)。应用治疗权重的逆概率来调整基线差异,最终分析11例TSR和23例SDR病例。我们评估了肾静脉长度和总体手术结局。

结果

SDR组的肾静脉长度明显长于TSR组(23.0 ± 4.0对17.5 ± 3.9 mm,P < 0.001)。然而,供体和受体的手术时间、估计失血量或围手术期并发症均无显著差异。两组间的热缺血时间、复温时间和总缺血时间也相当。受体组术后早期血清肌酐水平无显著差异。

结论

在右侧供肾肾切除术中,SDR吻合器在保留肾静脉长度方面具有显著的技术优势。然而,这并未转化为受体结局的改善,这表明手术精度和血管适应性在移植成功中比单纯的静脉长度起着更关键的作用。尽管如此,保留更长静脉长度的能力仍然是一个潜在优势,特别是在具有挑战性的病例中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1817/12208636/63abf7d1f9cc/txd-11-e1837-g001.jpg

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