Adebayo Ayobami, Ng Chester, Laroche Daniel
Department of Ophthalmology, Albert Einstein College of Medicine, Bronx, NY, United States.
Advanced Eyecare of NY, Manhattan, NY, United States.
Front Ophthalmol (Lausanne). 2025 Jun 16;5:1573937. doi: 10.3389/fopht.2025.1573937. eCollection 2025.
The Kahook Dual Blade goniotomy has been shown to be efficacious in the treatment of open angle glaucoma. We previously reported 6 months results using the Kahook Dual Blade in Black and Afro-Latino patients.
The purpose of this study was to determine the effectiveness and safety of Kahook Dual Blade (KDB) goniotomy alone or coupled with phacoemulsification cataract surgery to minimize intraocular pressure, number of medications used and visual field preservation in Black patients or Afro-Latinx who have open-angle glaucoma (OAG).
This was a retrospective, nonrandomized study that was carried out at two private practices in Harlem, NY and Queens, NY.
This study consisted of patients with OAG who underwent phacoemulsification combined with goniotomy (PE + KDB) or goniotomy alone (KDB). The Kahook dual blade was used to perform goniotomy in all patients. Reduction of intraocular pressure (IOP) and alleviating the burden of medications were both considered indications for glaucoma surgery. Our research included information on IOP before and after surgery, the number of medications to decrease IOP pressure, visual field mean deviation, during a follow-up period of two years.
At two years we identified 31 patients who had surgery. The preoperative IOP of all 31 eyes which had surgery was 16.7 mmHg which decreased to 14.0 mmHg after two years. The baseline number of topical IOP-lowering medications was 2.4 ± 1.4 at baseline which decreased to 1.6 ± 1.4 (P = 0.02) after two years. The average visual field mean deviation was stable in both groups after two years. Postoperative adverse events were mild and included transient hyphema, IOP spikes, posterior capsule opacification, tearing, glare and mild pain.
In Black or Afro-Latinx patients with open-angle glaucoma, phacoemulsification coupled with Kahook dual-blade goniotomy considerably reduces IOP and the number of medications.
已证明卡胡克双刃前房角切开术在开角型青光眼治疗中有效。我们之前报告了在黑人和非裔拉丁裔患者中使用卡胡克双刃的6个月结果。
本研究的目的是确定单独使用卡胡克双刃(KDB)前房角切开术或联合超声乳化白内障手术在降低眼压、减少用药数量以及保护黑人患者或患有开角型青光眼(OAG)的非裔拉丁裔患者视野方面的有效性和安全性。
这是一项在纽约哈莱姆区和皇后区的两家私人诊所进行的回顾性、非随机研究。
本研究纳入了接受超声乳化联合前房角切开术(PE + KDB)或单纯前房角切开术(KDB)的开角型青光眼患者。所有患者均使用卡胡克双刃进行前房角切开术。降低眼压(IOP)和减轻药物负担均被视为青光眼手术的指征。我们的研究包括手术前后眼压、降低眼压药物数量、视野平均偏差等信息,随访期为两年。
两年时,我们确定了31例接受手术的患者。所有31只接受手术眼睛的术前眼压为16.7 mmHg,两年后降至14.0 mmHg。基线时局部降眼压药物的平均数量为2.4 ± 1.4,两年后降至1.6 ± 1.4(P = 0.02)。两组患者两年后的平均视野平均偏差均保持稳定。术后不良事件较轻,包括短暂性前房积血、眼压峰值、后囊膜混浊、流泪、眩光和轻度疼痛。
在患有开角型青光眼的黑人或非裔拉丁裔患者中,超声乳化联合卡胡克双刃前房角切开术可显著降低眼压和减少用药数量。