Rossi F, Bellavite P, Berton G, Grzeskowiak M, Papini E
Pathol Res Pract. 1985 Aug;180(2):136-42. doi: 10.1016/S0344-0338(85)80161-8.
The paper deals with 1) the features of the respiratory burst (increase of the respiration with production of O2 metabolites, O2-, H2O2, OH) of the inflammatory cells; 2) the factors responsible for its activation; 3) the methods for its measurement; 4) the molecular events which take place at the level of the plasma membrane following the interaction between the stimuli and the cell surface (the Ca++ changes, the modification of membrane potential, the activation of phospholipid turnover) and the hypothesis of the activation of the protein kinase C; 5) the nature of the NADPH oxidase whose activation is responsible for the respiratory burst and the production of O2 metabolites; 6) the defensive, toxic, proinflammatory and modulatory effects due to the reactivity of the oxygen metabolites.
1）炎症细胞呼吸爆发的特征（呼吸增强并产生O2代谢产物O2-、H2O2、OH）；2）其激活的相关因素；3）测量方法；4）刺激与细胞表面相互作用后在质膜水平发生的分子事件（Ca++变化、膜电位改变、磷脂代谢激活）以及蛋白激酶C激活的假说；5）负责呼吸爆发和O2代谢产物产生的NADPH氧化酶的性质；6）氧代谢产物反应性所产生的防御、毒性、促炎和调节作用。
