未裂解（转化）滤泡中心细胞淋巴瘤的裂解细胞成分及其临床病理意义。

The cleaved cell content of non-cleaved (transformed) follicular center cell lymphomas and its clinico-pathological significance.

作者信息

Aine R, Alavaikko M

出版信息

Pathol Res Pract. 1985 Aug;180(2):181-4. doi: 10.1016/S0344-0338(85)80166-7.

Abstract

The relationship of cleaved cell content and survival was studied in 122 patients with transformed small and large non-cleaved cell types of the Lukes and Collins classification for non-Hodgkin's lymphomas. The large non-cleaved follicular center cell (FCC) type showed higher contents of cleaved cells than did the others; the geometric mean value differed significantly from that of small non-cleaved FCC Burkitt type (p less than 0.0001) or non-Burkitt type (p less than 0.01) lymphomas. There was a tendency toward a better prognosis with large fractions of cleaved cells but no statistical difference was found. The prognostic characteristics of the neoplastic clone are better revealed by the predominant cell.

摘要

在122例按照卢克斯和柯林斯分类法分为转化型小细胞和大细胞未分化型的非霍奇金淋巴瘤患者中，研究了裂解细胞含量与生存率的关系。大细胞未分化滤泡中心细胞（FCC）型显示出比其他类型更高的裂解细胞含量；几何平均值与小细胞未分化FCC伯基特型（p<0.0001）或非伯基特型（p<0.01）淋巴瘤的几何平均值有显著差异。裂解细胞比例高时有预后较好的趋势，但未发现统计学差异。肿瘤克隆的预后特征通过主要细胞能得到更好的揭示。