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[儿童B细胞淋巴瘤(B型非霍奇金淋巴瘤)——形态学和免疫学谱]

[B-cell lymphomas (non-Hodgkin's lymphomas of B type) in children--morphologic and immunologic spectrum].

作者信息

Schwarze E W, Pileri S, Stein H, Palestro G, Tolksdorf G

出版信息

Klin Padiatr. 1982 Jul-Aug;194(4):226-32. doi: 10.1055/s-2008-1033810.

Abstract

The non-Hodgkin's lymphomas (NHL) occurring in children are described on the basis of the Kiel classification. As a rule, the NHL in children are of high-grade malignancy. The morphologic and immunologic features of all types of high-grade malignant B-cell lymphoma are described. The most frequent type of B-NHL in children is B-lymphoblastic lymphoma, including Burkitt and non-Burkitt types. Centroblastic lymphoma, immunoblastic lymphoma and unclassified high-grade malignant NHL are less common in children. The difference between the morphologic term "unclassified" and the immunologic definition "non-B/non-T" or "null" (or "unclassified") is explained. The equivalents of the various lymphoma types in the Lukes-Collins and Rappaport classifications are given.

摘要

儿童非霍奇金淋巴瘤(NHL)依据基尔分类法进行描述。通常,儿童NHL具有高度恶性。文中描述了所有类型高度恶性B细胞淋巴瘤的形态学和免疫学特征。儿童中最常见的B-NHL类型是B淋巴母细胞淋巴瘤,包括伯基特型和非伯基特型。中心母细胞淋巴瘤、免疫母细胞淋巴瘤和未分类的高度恶性NHL在儿童中较少见。文中解释了形态学术语“未分类”与免疫学定义“非B/非T”或“无标记”(或“未分类”)之间的差异。还给出了各种淋巴瘤类型在卢克斯-柯林斯分类法和拉帕波特分类法中的对应类型。

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