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Serum Anti-Heart and Antinuclear Autoantibodies Are Independent Predictors of Response to Immunosuppressive Therapy in Autoimmune Biopsy-Proven Inflammatory Cardiomyopathy.

作者信息

Giordani Andrea Silvio, Baritussio Anna, Vicenzetto Cristina, Brigiari Gloria, Pilichou Kalliopi, Gregori Dario, De Gaspari Monica, Rizzo Stefania, Basso Cristina, Caforio Alida Linda Patrizia

机构信息

University of Padova, Padova, Italy.

University of Padova, Padova, Italy.

出版信息

JACC Basic Transl Sci. 2025 Jul;10(7):101310. doi: 10.1016/j.jacbts.2025.05.005.

DOI:10.1016/j.jacbts.2025.05.005
PMID:40592004
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12328274/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f06b/12328274/5ec9f04b5253/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f06b/12328274/5ec9f04b5253/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f06b/12328274/5ec9f04b5253/gr1.jpg

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Serum Anti-Heart and Antinuclear Autoantibodies Are Independent Predictors of Response to Immunosuppressive Therapy in Autoimmune Biopsy-Proven Inflammatory Cardiomyopathy.血清抗心脏和抗核自身抗体是自身免疫性活检证实的炎症性心肌病免疫抑制治疗反应的独立预测指标。
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本文引用的文献

1
Immunosuppressive therapy in virus-negative inflammatory cardiomyopathy: 20-year follow-up of the TIMIC trial.病毒阴性炎性心肌病的免疫抑制治疗:TIMIC 试验 20 年随访。
Eur Heart J. 2022 Sep 21;43(36):3463-3473. doi: 10.1093/eurheartj/ehac348.
2
Predictors of relapse, death or heart transplantation in myocarditis before the introduction of immunosuppression: negative prognostic impact of female gender, fulminant onset, lower ejection fraction and serum autoantibodies.在免疫抑制治疗引入之前,心肌炎复发、死亡或需要心脏移植的预测因素:女性、暴发性发作、射血分数降低和血清自身抗体与预后不良相关。
Eur J Heart Fail. 2022 Jun;24(6):1033-1044. doi: 10.1002/ejhf.2496. Epub 2022 Apr 19.
3
2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure.
2021年欧洲心脏病学会急性和慢性心力衰竭诊断与治疗指南。
Eur Heart J. 2021 Sep 21;42(36):3599-3726. doi: 10.1093/eurheartj/ehab368.
4
Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases.心肌炎的病因、诊断、治疗和治疗的现有知识状况:欧洲心脏病学会心肌和心包疾病工作组的立场声明。
Eur Heart J. 2013 Sep;34(33):2636-48, 2648a-2648d. doi: 10.1093/eurheartj/eht210. Epub 2013 Jul 3.
5
Prospective familial assessment in dilated cardiomyopathy: cardiac autoantibodies predict disease development in asymptomatic relatives.扩张型心肌病的前瞻性家族评估:心脏自身抗体可预测无症状亲属的疾病发展。
Circulation. 2007 Jan 2;115(1):76-83. doi: 10.1161/CIRCULATIONAHA.106.641472. Epub 2006 Dec 18.