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创伤性脑损伤后的保险类型与痴呆症诊断风险:对2000年至2022年期间267473名美国平民的研究

Insurance type and risk of dementia diagnosis after traumatic brain injury: a study of 267 473 US civilians from 2000 to 2022.

作者信息

Deshmukh Maya, Ugiliweneza Beatrice, Gilsanz Paola, Whitmer Rachel A, Boakye Maxwell, Nuño Miriam

机构信息

Department of Epidemiology, Columbia University Mailman School of Public Health, New York, New York, USA.

Department of Neurosurgery, University of Louisville, Louisville, Kentucky, USA.

出版信息

BMJ Open. 2025 Jul 1;15(7):e095893. doi: 10.1136/bmjopen-2024-095893.

Abstract

OBJECTIVES

To evaluate how insurance influences the risk of a dementia diagnosis among a large, diverse cohort of US civilian adults with traumatic brain injury (TBI) over a 22-year period.

DESIGN

This is a retrospective cohort study involving individuals diagnosed with TBI.

SETTING

The study used the Merative MarketScan Research Database, specifically drawing from the Commercial Claims and Encounters, Medicare Supplemental and Medicaid databases, from 2000 to 2022 in the USA. These databases provide comprehensive insights into healthcare services received by enrollees, including inpatient and outpatient services, outpatient prescription claims, clinical utilisation records and healthcare expenditures.

PARTICIPANTS

267 473 adults aged 55 and older who were diagnosed with a TBI between 1 January 2000 and 31 December 2022. Individuals with unknown TBI severity and dementia claims 2 years preceding TBI were excluded. TBI and dementia diagnoses were identified using International Classification of Disease 9th and 10th editions codes from inpatient and outpatient admission records.

INTERVENTIONS

None.

PRIMARY AND SECONDARY OUTCOME MEASURES

We compared the incidence of all-cause dementia across different insurance types to assess potential disparities in diagnosis following TBI. Cox proportional hazards models, with age as the time scale, were used to study the association between insurance type and dementia diagnosis following a TBI. Models were adjusted for key demographic variables, medical comorbidities and psychiatric conditions to account for potential confounding.

RESULTS

Of the 267 473 individuals with TBI, 12.7% were diagnosed with dementia over a mean follow-up period of 40 months (SD of 42 months). Dementia incidence differed significantly by insurance type, with 18.2% for Medicaid recipients, 17.3% for Medicare beneficiaries and only 2.3% among individuals with commercial insurance. The adjusted HR for dementia was notably higher among individuals enrolled on Medicaid (HR 2.9, 95% CI: 2.8 to 3.1) and Medicare (HR 2.1, 95% CI: 2.0 to 2.2), when compared with those with commercial insurance.

CONCLUSIONS

Individuals with TBI covered by Medicaid and Medicare are significantly more likely to be diagnosed with dementia, with a 2.9-fold and 2.1-fold increase risk, respectively, compared with those with commercial insurance. Addressing insurance-related disparities in dementia diagnosis is crucial for building a more equitable healthcare system. It is essential that individuals with TBI cases, regardless of their insurance type, have access to comprehensive care and preventive interventions to achieve the best possible long-term outcomes.

摘要

目的

评估在长达22年的时间里,保险如何影响美国一大群不同类型的患有创伤性脑损伤(TBI)的成年平民被诊断为痴呆症的风险。

设计

这是一项涉及被诊断为TBI的个体的回顾性队列研究。

背景

该研究使用了Merative MarketScan研究数据库,具体数据来自2000年至2022年美国的商业索赔与诊疗记录、医疗保险补充数据库和医疗补助数据库。这些数据库提供了参保者所接受医疗服务的全面信息,包括住院和门诊服务、门诊处方索赔、临床使用记录以及医疗支出。

参与者

267473名年龄在55岁及以上的成年人,他们在2000年1月1日至2022年12月31日期间被诊断为TBI。排除TBI严重程度未知以及在TBI发生前2年有痴呆症索赔的个体。使用来自住院和门诊入院记录的国际疾病分类第9版和第10版代码来确定TBI和痴呆症诊断。

干预措施

无。

主要和次要结局指标

我们比较了不同保险类型中全因痴呆症的发病率,以评估TBI后诊断方面的潜在差异。以年龄为时间尺度的Cox比例风险模型用于研究保险类型与TBI后痴呆症诊断之间的关联。模型针对关键人口统计学变量、医疗合并症和精神疾病进行了调整,以考虑潜在的混杂因素。

结果

在267473名患有TBI的个体中,在平均40个月(标准差为42个月)的随访期内,12.7%被诊断为痴呆症。痴呆症发病率因保险类型而异,医疗补助接受者为18.2%,医疗保险受益人中的发病率为17.3%,而商业保险个体中仅为2.3%。与商业保险个体相比,参加医疗补助(风险比2.9,95%置信区间:2.8至3.1)和医疗保险(风险比2.1,95%置信区间:2.0至2.2)的个体患痴呆症的调整后风险显著更高。

结论

与商业保险个体相比,参加医疗补助和医疗保险的TBI患者被诊断为痴呆症的可能性显著更高,风险分别增加了2.9倍和2.1倍。解决痴呆症诊断中与保险相关的差异对于建立更公平的医疗保健系统至关重要。无论保险类型如何,TBI患者都必须能够获得全面的护理和预防性干预措施,以实现尽可能好的长期结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9af7/12215115/16596d043ac7/bmjopen-15-7-g001.jpg

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