Khayami Mehdi, Rassoli Aisa, Feizkhah Alireza
Department of Mechanical Engineering, K. N. Toosi University of Technology, P.O. Box: 19395-19919, Tehran, Iran.
Burn and Regenerative Medicine Research Center, Guilan University of Medical Sciences, Rasht, Iran.
Sci Rep. 2025 Jul 1;15(1):21263. doi: 10.1038/s41598-025-04829-0.
Burns are among the most common injuries throughout history, and their treatment varies depending on the severity. Third-degree burns, the most severe and deadly type, cause numerous fatalities worldwide each year but can be treated using the skin mesh grafting technique-one of the latest advancements in burn care. However, an optimal skin mesh geometry has not yet been identified. This study aims to determine the best geometrical design for skin meshes by minimizing average stress, using Abaqus software for numerical analysis and extracting the hyperelastic mechanical properties of skin used in mesh grafts. Hyperelastic properties of healthy and meshed skin were obtained through uniaxial tensile tests, and different geometries were analyzed using Abaqus. The optimal mesh geometry was then determined using genetic algorithms in Abaqus and MATLAB. A rectangular mesh, measuring 1.939 mm in length and 1.698 mm in width, was identified as the best design with an average stress of 0.0757 MPa. These findings have potential applications in clinical burn research, contributing to the development of improved treatment methods.
烧伤是有史以来最常见的损伤之一,其治疗方法因严重程度而异。三度烧伤是最严重、最致命的烧伤类型,每年在全球导致众多死亡,但可以使用皮肤网状移植技术进行治疗,这是烧伤护理领域的最新进展之一。然而,尚未确定最佳的皮肤网状几何形状。本研究旨在通过最小化平均应力来确定皮肤网状物的最佳几何设计,使用Abaqus软件进行数值分析,并提取网状移植中使用的皮肤的超弹性力学性能。通过单轴拉伸试验获得健康皮肤和网状皮肤的超弹性性能,并使用Abaqus分析不同的几何形状。然后在Abaqus和MATLAB中使用遗传算法确定最佳网状几何形状。确定了一种矩形网状物,长1.939毫米,宽1.698毫米,为最佳设计,平均应力为0.0757兆帕。这些发现可能在临床烧伤研究中得到应用,有助于开发改进的治疗方法。