Xiao Huimin, Yao Rui, Liu Binbin, Duan Linrui, Liu Jincai, Lin Fen, Wang Siwang, Gao Jinming
College of Chemistry and Pharmacy, Northwest A&F University, Yangling, China.
Department of Life Science and Medicine, Northwest University, Xi'an, China.
Sci Rep. 2025 Jul 1;15(1):21739. doi: 10.1038/s41598-025-04860-1.
To evaluate the development and application of a kind of oil peony by chromatographic analysis of the main active components of the waste moutan pods (MP).The methods adopted in this paper, firstly, the quality evaluation method of MP is established by HPLC-DAD-ESI-MS/MS; The second is to compare the types and contents of the main active components of moutan barks (Chinese Pharmacopoeia, MB) with those of the medicinal parts of peony used in oil. HPLC fingerprint method for the extract of moutan pods (EMP) was established. Twenty-one compounds were identified in EMP and their levels determined in EMP and the extract of moutan barks (EMB) by HPLC. The results showed that the components of EMP and EMB were similar, though their contents differed. These findings suggest that EMP may have similar pharmacological effects to EMB. Our findings regarding the similarity and comparison of the chemical components in the EMB and EMP have important practical value for replacing EMB medicine and protecting peony plants from resource depletion caused by root digging.
通过对废弃牡丹荚果（MP）主要活性成分的色谱分析来评估一种油用牡丹的开发与应用。本文采用的方法，首先，通过HPLC-DAD-ESI-MS/MS建立MP的质量评价方法；其次，比较牡丹皮（《中国药典》，MB）与油用牡丹药用部位主要活性成分的种类和含量。建立了牡丹荚果提取物（EMP）的HPLC指纹图谱方法。通过HPLC在EMP中鉴定出21种化合物，并测定了EMP和牡丹皮提取物（EMB）中这些化合物的含量。结果表明，EMP和EMB的成分相似，但含量不同。这些发现表明，EMP可能具有与EMB相似的药理作用。我们关于EMB和EMP化学成分相似性及比较结果，对于替代EMB药材以及保护牡丹植株避免因采挖根部导致资源枯竭具有重要的实际价值。
