Bouhour J B, Lefevre M, Nicolas G, Horeau J
Arch Mal Coeur Vaiss. 1977 Apr;70(4):337-45.
Coarctation of the aorta is accompanied by congenital mitral incompetence in 3% of cases, and this combination worsens the prognosis. A series of 23 cases is reported, and the treatment analysed. In 6 cases only medical treatment was used, either because death was rapid or, on the contrary, satisfactory progress made it possible to wait for the normal age for resection and suture of the coarctation. In one case the severity of the mitral incompetence required early valvular replacement, while the minimal coarctation was ignored. Usually (16 cases) a Crafoord operation is carried out as a first stage, and of the 13 children still alive, 8 had their mitral incompetence improved or stabilised; but in 5 it became worse, requiring mitral valve surgery from 1 to 7 years later. Post mortem study showed the multiplicity of mitral lesions present, and explains the difficulty of mitral 'plasty' operations, which are the best solution in children.
主动脉缩窄在3%的病例中伴有先天性二尖瓣关闭不全,这种合并症会使预后恶化。本文报告了23例病例系列,并对其治疗情况进行了分析。6例仅采用了内科治疗,原因要么是死亡迅速,要么是相反,病情进展令人满意,使得能够等待进行主动脉缩窄切除和缝合的正常年龄。1例二尖瓣关闭不全的严重程度需要早期进行瓣膜置换,而轻微的主动脉缩窄则被忽略。通常(16例)作为第一阶段进行克拉夫德手术,在仍存活的13名儿童中,8例二尖瓣关闭不全得到改善或稳定;但5例病情恶化,需要在1至7年后进行二尖瓣手术。尸检研究显示存在多种二尖瓣病变,并解释了二尖瓣“成形”手术的困难,而二尖瓣“成形”手术是儿童的最佳解决方案。