Tsai Meng-Ju, Yang Chung-May, Yang Chang-Hao, Chen San-Ni, Sheu Shwu-Jiuan, Chen Shih-Jen, Ho Tzyy-Chang, Wu Tsung-Tien, Lai Chi-Chun, Cheng Cheng-Kuo
Department of Ophthalmology, Evergreen General Hospital, Taoyuan, Taiwan.
Department of Ophthalmology, Shin Kong Wu Ho-Su Memorial Hospital, No 95, Wen-chang Road, Shih-lin District, Taipei, Taiwan.
Sci Rep. 2025 Jul 1;15(1):20434. doi: 10.1038/s41598-025-06929-3.
To establish a consensus for surgical management of full-thickness macular hole (FTMH) and macular hole retinal detachment (MHRD). Nine experienced vitreoretinal surgeons from Taiwan participated in questionnaire for surgical management of FTMH and MHRD based on Delphi methodology. Among the 49 items, 30 items (61.2%) reached strong consensus after 2 rounds. For FTMH, strong consensus included routine internal limiting membrane (ILM) peeling in all stages of FTMH, ILM flap in large holes ≥ 400 μm, ILM flap covering technique, small peeling area < 5 mm diameter, preservation of adherent epiretinal membrane in the flap if it cannot be separated from ILM, CF as preferred tamponade for ILM peeling alone but not in the presence of ILM flap, post-operative facedown position, simple intravitreal gas injection for early persistent holes, use of pedicle flap or SWIFT for persistent holes in previously small area-peeled macula. For MHRD, strong consensus included the use of ILM flap, ILM flap covering technique, preservation of adherent epiretinal membrane if it cannot be separated from ILM, CF as preferred tamponade, post-operative facedown position, no intentional subretinal fluid drainage during air-fluid exchange in small RD area within arcade, intraoperative use of adjuvants. Strong consensus achieved in a significant portion of key questions frequently encountered in the management of FTMH and MHRD. Recommendations from this Delphi study helps in decision-making for clinical practice.
建立关于全层黄斑裂孔(FTMH)和黄斑裂孔性视网膜脱离(MHRD)手术治疗的共识。来自台湾的9位经验丰富的玻璃体视网膜外科医生基于德尔菲法参与了关于FTMH和MHRD手术治疗的问卷调查。在49个项目中,经过两轮后有30个项目(61.2%)达成了强烈共识。对于FTMH,强烈共识包括在FTMH各阶段常规进行内界膜(ILM)剥除、对于直径≥400μm的大裂孔采用ILM瓣、ILM瓣覆盖技术、直径<5mm的小剥除区域、如果不能与ILM分离则在瓣中保留附着的视网膜前膜、单独进行ILM剥除时CF作为首选填充剂但有ILM瓣时不适用、术后俯卧位、对于早期持续性裂孔进行简单的玻璃体内气体注射、对于先前小区域剥除的黄斑区持续性裂孔使用带蒂瓣或SWIFT。对于MHRD,强烈共识包括使用ILM瓣、ILM瓣覆盖技术、如果不能与ILM分离则保留附着的视网膜前膜、CF作为首选填充剂、术后俯卧位、在视网膜动脉弓内小视网膜脱离区域进行气液交换时不故意引流视网膜下液、术中使用辅助剂。在FTMH和MHRD管理中经常遇到的关键问题的很大一部分达成了强烈共识。这项德尔菲研究的建议有助于临床实践中的决策。