Machado-Fragua Marcos D, Fayosse Aurore, Dumurgier Julien, Kivimaki Mika, Ben Hassen Céline, Livingston Gill, Paquet Claire, Sabia Séverine, Singh-Manoux Archana
Université Paris Cité, Inserm U1153, Epidemiology of Ageing and Neurodegenerative Diseases, Paris, France.
Cognitive Neurology Center, Saint Louis-Lariboisiere-Fernand Widal Hospital, AP-HP, Université Paris Cité, Paris, France.
Nat Aging. 2025 Jul 1. doi: 10.1038/s43587-025-00914-1.
The prevalence of hearing impairment and dementia increases with age but the nature of their association remains unclear. Using data from two large UK-based cohort studies, we examined the longitudinal association of 'midlife' hearing impairment and hearing aid use with incident dementia. We found modest associations and population attributable fractions for reported and measured 'midlife' hearing impairment, highlighting the need to consider age at measurement of risk factors in studies that target dementia prevention.
听力障碍和痴呆症的患病率随年龄增长而增加，但其关联性质仍不明确。利用来自英国两项大型队列研究的数据，我们研究了“中年”听力障碍及助听器使用与痴呆症发病之间的纵向关联。我们发现，报告的和测量的“中年”听力障碍存在适度关联及人群归因分数，这凸显了在以痴呆症预防为目标的研究中考虑风险因素测量年龄的必要性。
