Ling Yaozheng, Sun Bingyue, Yin Guo, Ma Li, Li Yang, Meng Fanzheng, Gao Man
Department of Respiratory, Children's Medical Center, The First Hospital of Jilin University, Xinmin Street, Chaoyang District, Changchun, 130012, China.
Medical Insurance Office, The First Hospital of Jilin University, Xinmin Street, Chaoyang District, Changchun, 130012, China.
Sci Rep. 2025 Jul 1;15(1):21044. doi: 10.1038/s41598-025-07513-5.
Segmental/lobar pneumonia in children following Mycoplasma pneumoniae (MP) infection has a significant threat to the children's health, so early recognition of MP infection is critical to reduce the severity and improve the prognosis of segmental/lobar pneumonia in children. In this study, we aim to build predictive models using machine learning techniques to assist clinicians in the early identification of MP infection. We collected medical records of children with segmental/lobar pneumonia at the First Hospital of Jilin University between December 2016 and December 2021, and used four machine learning models for testing and validation. In this study, a total of 630 cases of children with segmental/lobar pneumonia were collected. After data pre-processing and feature selection, seven variables were used for prediction model construction. Four machine learning models were applied to predictive learning, and selecting Random Forest as a prediction model for MP infection after comprehensive selection, which achieved 57.1% sensitivity, 69.6% accuracy and 0.752 AUC. Based on machine learning algorithms, combined with conventional indicators of segmental/lobar pneumonia in children, to construct a prediction model for early identification of MP infection, which is of great help in assisting clinicians in early, targeted treatment.
肺炎支原体(MP)感染后儿童的节段性/大叶性肺炎对儿童健康构成重大威胁,因此早期识别MP感染对于降低儿童节段性/大叶性肺炎的严重程度和改善预后至关重要。在本研究中,我们旨在使用机器学习技术构建预测模型,以协助临床医生早期识别MP感染。我们收集了吉林大学第一医院2016年12月至2021年12月期间节段性/大叶性肺炎患儿的病历,并使用四种机器学习模型进行测试和验证。本研究共收集了630例节段性/大叶性肺炎患儿。经过数据预处理和特征选择后,使用七个变量构建预测模型。将四种机器学习模型应用于预测学习,综合筛选后选择随机森林作为MP感染的预测模型,其灵敏度为57.1%,准确率为69.6%,AUC为0.752。基于机器学习算法,结合儿童节段性/大叶性肺炎的常规指标,构建早期识别MP感染的预测模型,对协助临床医生进行早期、针对性治疗有很大帮助。