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波兰环境空气污染和气象因素对慢性阻塞性肺疾病(COPD)患者急诊入院的影响(2012 - 2019年)

The impact of ambient air pollution and meteorological factors on emergency hospital admissions of COPD patients in Poland (2012-2019).

作者信息

Bochenek Bogdan, Jankowski Mateusz, Wieczorek Joanna, Gruszczyńska Marta, Sekuła Piotr, Jaczewski Adam, Wyszogrodzki Andrzej, Pinkas Jarosław, Figurski Mariusz

机构信息

Institute of Meteorology and Water Management - National Research Institute, Division of Numerical Weather Prediction, Warsaw, Poland.

Centre of Postgraduate Medical Education, School of Public Health, Kleczewska 61/63 Street, Warsaw, 01-826, Poland.

出版信息

Sci Rep. 2025 Jul 1;15(1):21915. doi: 10.1038/s41598-025-07684-1.

Abstract

The relations between ambient air pollution, meteorological factors, and the number of emergency hospital admissions due to chronic obstructive pulmonary disease (COPD) were analyzed. The study utilized a nationwide collection of emergency hospital admissions from anonymous public registries covering the period of 8 years (2012-2019). Separated analyses were presented by sex, age group, and place of residence (rural vs. urban area), a group of major pollutants (PM2.5, PM10, SO, NO, and NO), and meteorological factors (daily air temperature minimum (Tmin), air temperature maximum (Tmax) and the daily change of an average air temperature (dTc), relative humidity (Rh) and wind speed (Ws)). This analysis confirmed association between environmental factors and an increase in the number of emergency hospital admissions of COPD patients. The greatest correlations (p < 0.001) were r = 0.58 and day lag = 5 days for PM10, r = 0.63 and day lag = 20 days for PM2.5, r = 0.73 and day lag = 20 days for SO, r = 0.57 and day lag = 25 days for NO and r = 0.51 and day lay = 30 for NOx as well as r = -0.78 and day lag = 19 days for Tmax, r = -0.79 and day lag = 19 days for Tmin, r =  - 0.57 and day lag = 22 days for dTc, r = 0.42 and day lag = 30 days for Rh and r = 0.40 and day lay = 14 for Ws. Variations of SO and temperature were the most important factors associated with emergency hospital admissions of COPD patients in Poland. Women, patients aged 60-79 as well as inhabitants of urban areas showed stronger and faster responses to changes in environmental elements.

摘要

分析了环境空气污染、气象因素与慢性阻塞性肺疾病(COPD)急诊住院人数之间的关系。该研究利用了来自匿名公共登记处的全国性急诊住院数据收集,涵盖8年时间(2012 - 2019年)。按性别、年龄组和居住地(农村与城市地区)、一组主要污染物(PM2.5、PM10、SO、NO和NOx)以及气象因素(每日最低气温(Tmin)、最高气温(Tmax)和平均气温的日变化(dTc)、相对湿度(Rh)和风速(Ws))进行了单独分析。该分析证实了环境因素与COPD患者急诊住院人数增加之间的关联。最大相关性(p < 0.001)为:PM10的r = 0.58且滞后天数 = 5天,PM2.5的r = 0.63且滞后天数 = 20天,SO的r = 0.73且滞后天数 = 20天,NO的r = 0.57且滞后天数 = 25天,NOx的r = 0.51且滞后天数 = 30天,以及Tmax的r = -0.78且滞后天数 = 19天,Tmin的r = -0.79且滞后天数 = 19天,dTc的r = -0.57且滞后天数 = 22天,Rh的r = 0.42且滞后天数 = 30天,Ws的r = 0.40且滞后天数 = 14天。在波兰,SO和温度的变化是与COPD患者急诊住院相关的最重要因素。女性、60 - 79岁的患者以及城市居民对环境因素变化的反应更强且更快。

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