Kentera D, Zdravković M, Rolović Z, Susić D
Respiration. 1985;48(2):159-63. doi: 10.1159/000194817.
A study of the platelet count in rats exposed to normobaric hypoxia for 4 weeks revealed that hypoxia alone, without any change in barometric pressure, considerably reduced the number of thrombocytes. In order to elucidate the mechanism of hypoxic thrombocytopenia, the survival and recovery of 51Cr-labelled platelets were tested. The survival and recovery of platelets from hypoxic rats injected into normoxic recipients were normal. However, when 51Cr-labelled platelets from normoxic rats were injected into a hypoxic recipient, the survival was found to be normal but the recovery of those platelets was lower than in the normal rat. This finding suggests that the reduction of platelet counts in normobaric hypoxia may be due to the platelets' partial sequestration.
一项对暴露于常压缺氧环境4周的大鼠血小板计数的研究表明，仅缺氧而气压无任何变化时，会显著减少血小板数量。为了阐明缺氧性血小板减少的机制，对51Cr标记的血小板的存活和恢复情况进行了测试。将缺氧大鼠的血小板注射到常氧受体中，其存活和恢复情况正常。然而，当将常氧大鼠的51Cr标记血小板注射到缺氧受体中时，发现其存活正常，但这些血小板的恢复率低于正常大鼠。这一发现表明，常压缺氧时血小板计数的减少可能是由于血小板的部分滞留所致。
