Zhou Li, Gu Xi, Tan Feilong, Li Yanhua, Duanmu Wenjing, Che Hongyi, Yang Fan, Yin Wenjie
Department of Pharmacy, The Affiliated Yan'an Hospital of Kunming Medical University, Kunming, China.
Joint Surgery, General Hospital of Xizang Military Command, Lhasa, China.
BMC Health Serv Res. 2025 Jul 1;25(1):853. doi: 10.1186/s12913-025-12901-8.
Implementing a full-sample prescription review system has become imperative for hospitals to address the limitations of post-review practices and ensure patient medication safety. In this study, we investigate the preliminary application impact of the prescription pre-review system (PPRS)and its rules maintenance in our hospital, while also evaluating the pharmaceutical service value resulting from the implementation of prescription pre-review.
We incorporated levels of prescribing warnings into the PPRS, while establishing and maintaining a database of appropriate medication practices. In addition, we evaluated the rationality of intravenous infusion prescriptions and key monitored drug prescriptions before and after the implementation of PPRS, and briefly evaluated the irrational prescriptions.
A comprehensive range of 7 warning levels was established, reflective of the degree of prescription irrationality. Besides, a total of 3015 user rules were created to regulate medication behavior. The number and proportion of unreasonable prescriptions during January to March 2023 demonstrated a noteworthy reduction when compared to the corresponding period in 2022. Moreover, the continuous evaluation of systematic alert prescriptions during January to March 2023 indicated a remarkable monthly decline.
The introduction of the PPRS has ushered in a paradigm shift in the evaluation of prescription rationality. This transformative system has played a pivotal role in standardizing doctor’s prescribing patterns, thereby promoting the rational utilization of drugs in clinical practice. By ensuring patient safety, elevating the quality of care, and enhancing the value of pharmacists, the PPRS has emerged as a catalyst for positive change in the healthcare setting.
The online version contains supplementary material available at 10.1186/s12913-025-12901-8.
实施全样本处方审核系统已成为医院解决事后审核做法的局限性并确保患者用药安全的当务之急。在本研究中，我们调查了处方预审核系统（PPRS）及其规则维护在我院的初步应用影响，同时评估了处方预审核实施所带来的药学服务价值。
我们将处方警示级别纳入PPRS，同时建立并维护一个合理用药实践数据库。此外，我们评估了PPRS实施前后静脉输液处方和重点监测药物处方的合理性，并简要评估了不合理处方。
建立了全面的7个警示级别，反映了处方不合理的程度。此外，共创建了3015条用户规则来规范用药行为。与2022年同期相比，2023年1月至3月期间不合理处方的数量和比例显著减少。此外，对2023年1月至3月期间系统警示处方的持续评估表明每月有显著下降。
PPRS的引入在处方合理性评估方面带来了范式转变。这个变革性的系统在规范医生处方模式方面发挥了关键作用，从而促进了临床实践中药物的合理使用。通过确保患者安全、提高护理质量和提升药师价值，PPRS已成为医疗环境中积极变革的催化剂。
在线版本包含可在10.1186/s12913 - 025 - 12901 - 8获取的补充材料。
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