Ruiz-Sánchez Francisco Javier, Martins Maria do Rosário, Losa-Iglesias Marta Elena, Becerro-de-Bengoa-Vallejo Ricardo, Gómez-Salgado Juan, Saavedra-García Miguel Ángel, López-López Daniel, Jiménez-Cebrián Ana María
Department of Health Sciences, Faculty of Nursing and Podiatry, Industrial Campus of Ferrol, Research, Health and Podiatry Group, Universidade da Coruña, Ferrol, Spain.
UICISA:E; Instituto Politécnico de Viana do Castelo, Viana do Castelo, Portugal.
J Foot Ankle Res. 2025 Sep;18(3):e70061. doi: 10.1002/jfa2.70061.
Multiple sclerosis (MS) is a complex early-onset neurological disorder with significant functional implications. Neuroinflammation and neurodegeneration are the primary pathological processes underlying MS, both of which may alter lower limb loading patterns. These alterations can be evaluated through static plantar pressure distribution. This study hypothesized that patients with MS would exhibit higher static plantar pressures compared to healthy controls.
A multicenter case-control study was conducted with 88 participants, comprising 44 patients diagnosed with MS and 44 age- and sex-matched healthy controls. Static plantar pressures were assessed using the PodoPrint Aluminum pressure platform.
The MS group demonstrated significantly lower maximum peak pressure values in both the right foot (p < 0.007) and the left foot (p < 0.001) compared to the control group.
A marked reduction in maximum peak pressures and weight-bearing capacity was observed in patients with MS may have reduced plantar pressure, which could be indicative of altered gait patterns and balance issues.
多发性硬化症(MS)是一种复杂的早发性神经疾病,具有重大的功能影响。神经炎症和神经退行性变是MS的主要病理过程,两者都可能改变下肢负荷模式。这些改变可以通过静态足底压力分布来评估。本研究假设,与健康对照组相比,MS患者会表现出更高的静态足底压力。
进行了一项多中心病例对照研究,共有88名参与者,包括44名被诊断为MS的患者和44名年龄及性别匹配的健康对照者。使用PodoPrint铝制压力平台评估静态足底压力。
与对照组相比,MS组右脚(p < 0.007)和左脚(p < 0.001)的最大峰值压力值均显著降低。
观察到MS患者的最大峰值压力和承重能力显著降低,可能足底压力降低,这可能表明步态模式改变和平衡问题。