Ruiz-Sánchez Francisco Javier, do Rosário Martins Maria, Soares Salete, Romero-Morales Carlos, López-López Daniel, Gómez-Salgado Juan, Jiménez-Cebrián Ana María
Research, Health and Podiatry Group, Department of Health Sciences, Faculty of Nursing and Podiatry, Industrial Campus of Ferrol, Universidade da Coruña, 15403 Ferrol, Spain.
UICISA:E, Escola Superior de Saúde, Instituto Politécnico de Viana do Castelo, Rua D. Moisés Alves Pinho 190, 4900-314 Viana do Castelo, Portugal.
Healthcare (Basel). 2022 Nov 4;10(11):2218. doi: 10.3390/healthcare10112218.
Multiple sclerosis (MS) is a neurological, chronic, inflammatory, and progressive disease with musculoskeletal problems and neurodegenerative disorders that causes worsening of the health status of patients. The aim of this study was to determine the level of depression in MS patients compared to a population of healthy subjects. The established sample size was 116 subjects matched with the same age, sex, and body mass index. The subjects were recruited from different multiple sclerosis associations and neurology clinics in different public health areas (case group n = 58) and healthy subjects from the same locality (control group n = 58). The scores and categories of the Beck Depression Inventory (BDI) in its Spanish version were collected. There was a clear statistically significant difference (p < 0.05) in the BDI scores between both groups. As a result, we found that the subjects with MS presented worse results with BDI = 9.52 ± 7.70 points compared to the healthy subjects with a BDI score = 5.03 ± 5.14. Within the BDI categories, there were statistically significant differences (p < 0.001), which were greater for the MS group. Depression is a dangerous factor for MS patients, being a trigger for a poorer quality of life.
多发性硬化症（MS）是一种神经系统慢性炎症性进行性疾病，伴有肌肉骨骼问题和神经退行性疾病，会导致患者健康状况恶化。本研究的目的是确定与健康受试者群体相比，MS患者的抑郁水平。确定的样本量为116名年龄、性别和体重指数相匹配的受试者。受试者来自不同公共卫生区域的多个多发性硬化症协会和神经科诊所（病例组n = 58）以及来自同一地区的健康受试者（对照组n = 58）。收集了西班牙语版贝克抑郁量表（BDI）的得分和类别。两组之间的BDI得分存在明显的统计学显著差异（p < 0.05）。结果，我们发现MS患者的BDI得分为9.52 ± 7.70分，明显低于健康受试者的BDI得分5.03 ± 5.14分。在BDI类别中，存在统计学显著差异（p < 0.001），MS组的差异更大。抑郁是MS患者的一个危险因素，会引发生活质量下降。
