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非甾体抗炎药使用情况的知晓度:一项横断面研究。

Awareness of the use of non-steroidal anti-inflammatory drugs: A cross-sectional study.

作者信息

Chkhikvadze Lasha, Chikobava Elisabed, Hariharan Nithesh, Omprakash Amritha, Aamil Syed Mohammed

机构信息

American MD Program, Tbilisi State Medical University, 0186 Tbilisi, Georgia.

出版信息

Med Int (Lond). 2025 Jun 16;5(5):49. doi: 10.3892/mi.2025.248. eCollection 2025 Sep-Oct.

Abstract

Non-steroidal anti-inflammatory drugs (NSAIDs) are widely utilized across the globe and are frequently used without prescription for various therapeutic purposes. Given their potential for severe adverse effects, assessing the awareness of the use of NSAIDs is crucial. The present study evaluated the awareness levels of the use of NSAID among consumers through a descriptive, cross-sectional, non-randomized study. A 33-item online survey was conducted with 385 NSAID consumers aged ≥18 years between August and October, 2023. Awareness levels were determined based on knowledge and attitude scores assigned to correct responses. The results revealed that headaches (62.9%) and menstrual pain (32.4%) were the primary reasons for the use of NSAIDs, with ibuprofen being the preferred generic NSAID. The overall knowledge of NSAIDs was found to be inadequate, particularly concerning associated risks, such as stroke and myocardial infarction, despite a good understanding of the gastrointestinal risks. Female participants, those aged 26-45 years, and individuals with higher education levels demonstrated better knowledge. A concerning tendency toward self-administration and over-the-counter use was observed. These findings highlight the need for targeted educational initiatives and regulatory interventions to improve NSAID awareness and promote responsible medication practices.

摘要

非甾体抗炎药(NSAIDs)在全球范围内被广泛使用,并且经常在没有处方的情况下用于各种治疗目的。鉴于其存在严重不良反应的可能性,评估NSAIDs使用的知晓情况至关重要。本研究通过一项描述性、横断面、非随机研究评估了消费者对NSAIDs使用的知晓水平。2023年8月至10月期间,对385名年龄≥18岁的NSAIDs消费者进行了一项包含33个项目的在线调查。知晓水平是根据对正确回答所赋予的知识和态度得分来确定的。结果显示,头痛(62.9%)和痛经(32.4%)是使用NSAIDs的主要原因,布洛芬是首选的非专利NSAID。尽管对胃肠道风险有较好的了解,但发现对NSAIDs的总体知识不足,尤其是关于中风和心肌梗死等相关风险。女性参与者、年龄在26 - 45岁之间的人以及受过高等教育的人表现出更好的知识水平。观察到存在自行用药和非处方用药的令人担忧的趋势。这些发现凸显了开展有针对性的教育举措和监管干预措施以提高NSAIDs知晓度并促进合理用药实践的必要性。

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