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一名非免疫功能低下患者因[未提及具体病因]导致膈下脓肿的罕见病例报告。

A rare presentation of subphrenic abscess caused by in a non-immunocompromised patient: A case report.

作者信息

Chkhikvadze Lasha, Chikobava Elisabed, Kantaria Nino

机构信息

American MD Program, Tbilisi State Medical University, 0186 Tbilisi, Georgia.

Department of Internal Medicine, New Hospitals, 0162 Tbilisi, Georgia.

出版信息

Med Int (Lond). 2025 Jun 17;5(5):50. doi: 10.3892/mi.2025.249. eCollection 2025 Sep-Oct.

DOI:10.3892/mi.2025.249
PMID:40599154
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12207833/
Abstract

Subphrenic abscesses are rare, yet clinically significant, and are often associated with intra-abdominal infections. The present case report describes the case of a 77-year-old male patient with an unusual presentation of a subphrenic abscess caused by without typical predisposing factors. The patient experienced a prolonged 2-year course characterized by recurrent febrile episodes and respiratory symptoms. The diagnosis was confirmed through imaging and microbiological culture, with percutaneous drainage and culture-directed antibiotic therapy, including meropenem, leading to successful treatment. The multidrug-resistant nature of the pathogen, coupled with the atypical presentation of the patient, posed significant challenges in both diagnosis and management. The case described herein underscores the importance of comprehensive diagnostic imaging, timely intervention and individualized treatment strategies in managing such complex infections.

摘要

膈下脓肿虽罕见,但具有临床意义,且常与腹腔内感染相关。本病例报告描述了一名77岁男性患者,其膈下脓肿表现不寻常,无典型的易感因素。患者病程长达两年,以反复发热和呼吸道症状为特征。通过影像学和微生物培养确诊,采用经皮引流和针对性抗生素治疗,包括美罗培南,治疗成功。病原体的多重耐药性以及患者的非典型表现给诊断和治疗带来了重大挑战。本文所述病例强调了在处理此类复杂感染时综合诊断成像、及时干预和个体化治疗策略的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e69c/12207833/ecff68b3559c/mi-05-05-00249-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e69c/12207833/ecff68b3559c/mi-05-05-00249-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e69c/12207833/ecff68b3559c/mi-05-05-00249-g00.jpg

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本文引用的文献

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Evolution of β-Lactam Antibiotic Resistance in Species: From Extended-Spectrum and Plasmid-Mediated AmpC β-Lactamases to Carbapenemases.β-内酰胺类抗生素在物种中的耐药性演变:从超广谱和质粒介导的AmpC β-内酰胺酶到碳青霉烯酶
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Radiol Med. 2021 Dec;126(12):1561-1570. doi: 10.1007/s11547-021-01406-z. Epub 2021 Aug 20.
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Intracranial Abscess and Proteus mirabilis: A Case Report and Literature Review.颅内脓肿与奇异变形杆菌:一例报告及文献综述
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