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同一患者在五天内发生两次急性ST段抬高型心肌梗死和两次急性缺血性脑卒中——哪里出了问题?

TWO ACUTE STEMIS AND TWO ACUTE ISCHEMIC STROKES IN THE SAME PATIENT WITHIN FIVE DAYS - WHAT WENT WRONG?

作者信息

Slivnjak Valentina, Šesto Igor, Jelić Alan, Kalousek Vladimir, Cerovec Dora, Škopljanac Mačina Andrija, Štambuk Krešimir

机构信息

Magdalena Clinic for Cardiovascular Disease, Krapinske Toplice, at Faculty of Medicine, JJ Strossmayer University in Osijek, Osijek, Croatia.

Faculty of Dental Medicine and Health, J.J. Strossmayer University in Osijek, Osijek, Croatia.

出版信息

Acta Clin Croat. 2024 Mar;63(Suppl1):90-95. doi: 10.20471/acc.2024.63.s1.17.

Abstract

It is not uncommon for patients to suffer from both acute myocardial infarction and acute stroke during the hospitalization. According to some studies, about 12% of the elderly population initially hospitalized for acute ischemic stroke also develop type-1 acute myocardial infarction during the same hospitalization. On the other hand, about 0.9% of patients hospitalized for acute coronary syndrome develop acute stroke during the same hospitalization1. The therapeutic approach to such "overlapping" patients is challenging, especially if we also take into account a high risk of bleeding and/or active bleeding. Therefore, interdisciplinary collaboration between cardiology, neurology and interventional neuroradiology is of key importance. Timely intervention and adequate concomitant drug therapy (primarily antiplatelet and anticoagulant therapy) determine treatment outcomes and long-term results. In our recent clinical work, we treated a patient with a series of acute cardiac and cerebral incidents presenting multiple therapeutic dilemmas, who ultimately had an unfavourable neurological outcome.

摘要

患者在住院期间同时患有急性心肌梗死和急性中风的情况并不少见。根据一些研究,约12%最初因急性缺血性中风住院的老年人群在同一住院期间也会发生1型急性心肌梗死。另一方面,约0.9%因急性冠状动脉综合征住院的患者在同一住院期间发生急性中风。对于这类“重叠”患者的治疗方法具有挑战性,尤其是当我们还要考虑到出血高风险和/或活动性出血时。因此,心脏病学、神经病学和介入神经放射学之间的跨学科合作至关重要。及时干预和适当的联合药物治疗(主要是抗血小板和抗凝治疗)决定治疗结果和长期效果。在我们最近的临床工作中,我们治疗了一名出现一系列急性心脏和脑部事件并呈现多个治疗困境的患者,该患者最终出现了不利的神经学结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a379/12207856/9983058fcf31/acc-63_supp1-90-f1.jpg

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