Mahmoud Adil A, Elnour Asim Ahmed, Saeed Ali Awadallah, Menon Vineetha, Elhag Shereen A M, Fathi G Omkalthoum, Ayoup M Mohamed, Abdulhadi M A Hussam, Sameer E Ahmed, Tahaa E Mohamed, Beshir Semira Abdi, Al Mazrouei Nadia, Abdalla Sami Fatehi, Alsulami Fahad T, Alqarni Yousef Saeed, Mohammed Abuelnor
Department of Pharmacy Practice, Faculty of Clinical and Industrial Pharmacy, National University-Sudan, Khartoum, Sudan.
Program of Clinical Pharmacy, College of Pharmacy, Al Ain University, Abu Dhabi, United Arab Emirates (UAE).
J Pharm Policy Pract. 2025 Jun 30;18(1):2519140. doi: 10.1080/20523211.2025.2519140. eCollection 2025.
Specific actions to promote the RUD in public and private hospitals are highly needed. The current study aimed to assess RUD based on World Health Organization (WHO) prescribing indicators in selected public and private hospitals in Khartoum state-Sudan.
A multicenter cross-sectional study was conducted in six public and three private hospitals. After ethics approval, a consecutive random sample of 2880 patient encounter prescriptions was selected. The IRDP indicates adherence to RUD.
The average number of drugs per patient encounter prescription was 1.7 ± 0.2 and 2.5 ± 0.2 (overall 2.1) in public and private hospitals, respectively. Drugs prescribed generically were 61% (index 0.61) in public hospitals and 24% (index 0.24) in private hospitals. The index of injection prescribing was 0.1 for public and 0.85 for private hospitals. Drugs on the EDL accounted for 94% of prescriptions in public hospitals and 70% in private hospitals. The EDL prescribing index was 0.94 for public and 0.7 for private hospitals. The overall mean IRDP for public and private hospitals was 3.11.
Inadequate prescribing patterns in public and private hospitals significantly deviate from WHO standards across most prescribing indicators. Consequently, public and private hospitals should strive to promote the RUD.
在公立和私立医院中非常需要采取具体行动来促进合理用药。本研究旨在根据世界卫生组织（WHO）的处方指标，对苏丹喀土穆州选定的公立和私立医院的合理用药情况进行评估。
在六家公立医院和三家私立医院开展了一项多中心横断面研究。获得伦理批准后，连续随机抽取了2880份患者就诊处方。不合理用药率（IRDP）表明对合理用药的依从性。
公立和私立医院中，每份患者就诊处方的平均用药数量分别为1.7±0.2和2.5±0.2（总体为2.1）。公立医院中采用通用名开具的药物占61%（指数为0.61），私立医院中这一比例为24%（指数为0.24）。公立医院的注射剂处方指数为0.1，私立医院为0.85。基本药物清单（EDL）上的药物在公立医院的处方中占94%，在私立医院中占70%。公立医院的EDL处方指数为0.94，私立医院为0.7。公立和私立医院的总体平均不合理用药率为3.11。
公立和私立医院的处方模式存在不足，在大多数处方指标上显著偏离了WHO标准。因此，公立和私立医院应努力促进合理用药。
