Nakiri Makoto, Kurose Hirofumi, Komine Shinnosuke, Suekane Hiroki, Chikui Katsuaki, Ueda Kosuke, Uemura Keiichiro, Nishihara Kiyoaki, Muraki Koichiro, Hattori Chikayuki, Ogo Etsuyo, Igawa Tsukasa
Department of Urology, Kurume University School of Medicine, Kurume, Japan.
Department of Radiology, Kurume University School of Medicine, Kurume, Japan.
Urol Case Rep. 2025 Jun 16;61:103097. doi: 10.1016/j.eucr.2025.103097. eCollection 2025 Jul.
Salvage therapy is effective for treating local recurrence following radiation therapy for prostate cancer. Although surgery, radiation therapy, and hormonal therapy can be considered as options for salvage therapy for seminal vesicle recurrence of prostate cancer, there are reports of poor outcomes, and many cases involve treatment difficulties and post-treatment recurrence. In this article, we report our findings on the use of trimodality therapy, consisting of salvage focal brachytherapy, intensity-modulated radiation therapy, and hormonal therapy, in a patient who showed seminal vesicle recurrence 10 years after brachytherapy, with no major adverse events and no biochemical recurrence over 5 years.
挽救性治疗对前列腺癌放疗后局部复发有效。虽然手术、放疗和激素治疗可被视为前列腺癌精囊复发挽救性治疗的选择，但有报道称治疗效果不佳，且许多病例存在治疗困难和治疗后复发的情况。在本文中，我们报告了对一名在近距离放疗10年后出现精囊复发的患者采用挽救性局部近距离放疗、调强放疗和激素治疗组成的三联疗法的研究结果，该患者5年内无重大不良事件且无生化复发。
