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未诊断出的血小板减少症所致医源性脊髓硬膜下血肿:一例罕见的类似肿瘤的延迟诊断病例。

Iatrogenic spinal subdural hematoma in undiagnosed thrombocytopenia: A rare case of delayed diagnosis mimicking neoplasm.

作者信息

Gupta Kaustubh, Raj Gaurav, Kumar Tushant, Sonkar Shailly

机构信息

Department of Radio-diagnosis, Dr. RMLIMS, Lucknow, Uttar Pradesh, India.

出版信息

Radiol Case Rep. 2025 Jun 16;20(9):4409-4412. doi: 10.1016/j.radcr.2025.05.067. eCollection 2025 Sep.

DOI:10.1016/j.radcr.2025.05.067
PMID:40600119
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12209904/
Abstract

Spinal subdural hematomas following lumbar puncture are rare but serious complications, typically associated with coagulopathies. We report a case of a 27-year-old male who developed progressive lower limb weakness and urinary incontinence after undergoing a diagnostic lumbar puncture at an outside facility. MRI spine initially suggested an intradural neoplasm due to clumped nerve roots and abnormal signal, delaying diagnosis. Further evaluation revealed previously undiagnosed thrombocytopenia (platelet count <30,000). The patient was managed conservatively following platelet transfusion with eventual neurological improvement. This case highlights the critical need for preprocedural coagulation screening and the diagnostic challenges posed by atypical imaging presentations of spinal hematoma.

摘要

腰椎穿刺后发生的脊髓硬膜下血肿是罕见但严重的并发症,通常与凝血病相关。我们报告一例27岁男性病例,该患者在外部机构接受诊断性腰椎穿刺后出现进行性下肢无力和尿失禁。脊柱MRI最初因神经根聚集和信号异常提示硬膜内肿瘤,从而延误了诊断。进一步评估发现此前未诊断出的血小板减少症(血小板计数<30,000)。患者在输注血小板后接受保守治疗,最终神经功能得到改善。该病例凸显了术前凝血筛查的迫切需求以及脊髓血肿非典型影像学表现所带来的诊断挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9859/12209904/8ba0fb2560b6/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9859/12209904/537ad8c51d97/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9859/12209904/63a06574e46e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9859/12209904/40c975a78064/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9859/12209904/bbb2e72cd10f/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9859/12209904/8ba0fb2560b6/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9859/12209904/537ad8c51d97/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9859/12209904/63a06574e46e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9859/12209904/40c975a78064/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9859/12209904/bbb2e72cd10f/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9859/12209904/8ba0fb2560b6/gr5.jpg

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本文引用的文献

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MR imaging of spinal haematoma: a pictorial review.脊柱血肿的磁共振成像:图谱综述
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Iatrogenic spinal hematoma as a complication of lumbar puncture: What is the risk and best management plan?医源性脊髓血肿作为腰椎穿刺的并发症:风险是什么以及最佳管理方案是什么?
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Spinal hematoma: a literature survey with meta-analysis of 613 patients.脊髓血肿:一项对613例患者进行荟萃分析的文献综述
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Spinal subdural haematoma: a study of three cases.脊髓硬膜下血肿:三例病例研究
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