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脑动脉瘤的当前治疗方法:是基于事实还是误解?

Current management of cerebral aneurysms: is it based on facts or myths?

作者信息

Ausman J I, Diaz F G, Malik G M, Fielding A S, Son C S

出版信息

Surg Neurol. 1985 Dec;24(6):625-35. doi: 10.1016/0090-3019(85)90120-x.

DOI:10.1016/0090-3019(85)90120-x
PMID:4060041
Abstract

The overall morbidity and mortality from aneurysmal subarachnoid hemorrhage have not changed significantly over the past 30 years in spite of great progress in surgical technology and diagnostic capabilities. Most series report major morbidity and mortality figures of approximately 60%. The reason for the currently poor prognosis is due, in part, to the sometimes devastating effect of the initial hemorrhage over which we have no control. Another reason for our inability to improve these dismal statistics may be that the currently accepted treatment regimens have proven to be ineffective. Eighteen misconceptions or "myths" surrounding the treatment of aneurysmal subarachnoid hemorrhage have been identified as factors that have largely determined the currently accepted, ineffective treatment protocols, and these are discussed.

摘要

尽管在外科技术和诊断能力方面取得了巨大进展,但在过去30年中,动脉瘤性蛛网膜下腔出血的总体发病率和死亡率并未显著改变。大多数系列报道的主要发病率和死亡率数字约为60%。目前预后不佳的部分原因在于初始出血有时会产生毁灭性影响,而对此我们无法控制。我们无法改善这些令人沮丧的统计数据的另一个原因可能是,目前公认的治疗方案已被证明无效。围绕动脉瘤性蛛网膜下腔出血治疗存在的18个误解或“误区”已被确定为在很大程度上决定了目前公认的无效治疗方案的因素,并将对这些误解进行讨论。

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Current management of cerebral aneurysms: is it based on facts or myths?脑动脉瘤的当前治疗方法:是基于事实还是误解?
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2
Vasodilators during cerebral aneurysm surgery.
Can J Anaesth. 1993 Aug;40(8):775-90. doi: 10.1007/BF03009775.
3
Aneurysmal bleeding. A plea for early surgery in good-risk patients.动脉瘤性出血。呼吁对高危患者尽早进行手术。
Acta Neurochir (Wien). 1994;128(1-4):126-31. doi: 10.1007/BF01400662.
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Traumatic intracranial aneurysms in childhood and adolescence. Case reports and review of the literature.儿童和青少年创伤性颅内动脉瘤。病例报告及文献综述。
Childs Nerv Syst. 1994 Aug;10(6):361-79. doi: 10.1007/BF00335125.
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Benign subarachnoid haemorrhage (subarachnoid haemorrhage of unknown aetiology).良性蛛网膜下腔出血(病因不明的蛛网膜下腔出血)。
Acta Neurochir (Wien). 1987;86(3-4):89-92. doi: 10.1007/BF01402290.
6
Does the timing of aneurysm surgery neglect the real problems of subarachnoid haemorrhage?
Acta Neurochir (Wien). 1987;89(3-4):91-9. doi: 10.1007/BF01560372.
7
Results of treatment for cerebral saccular aneurysms in a small neurosurgical unit--evaluation of early operation and nimodipine treatment.
Acta Neurochir (Wien). 1988;94(1-2):28-31. doi: 10.1007/BF01406611.
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Timing of aneurysm surgery. Comparison of results of early and delayed surgical intervention.动脉瘤手术时机。早期与延迟手术干预结果的比较。
Eur Arch Psychiatry Neurol Sci. 1988;237(5):291-7. doi: 10.1007/BF00450548.
9
Ultrastructural changes of the basilar artery following experimental subarachnoid haemorrhage. A morphological study on the pathogenesis of delayed cerebral vasospasm.实验性蛛网膜下腔出血后基底动脉的超微结构变化。关于迟发性脑血管痉挛发病机制的形态学研究。
Acta Neurochir (Wien). 1989;100(3-4):164-71. doi: 10.1007/BF01403606.
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Haemodynamic considerations in the management of patients with subarachnoid haemorrhage.蛛网膜下腔出血患者管理中的血流动力学考量
Can J Anaesth. 1991 May;38(4 Pt 1):454-70. doi: 10.1007/BF03007583.