坦桑尼亚临床分离株的基因组特征分析
Genomic characterization of clinical isolates from Tanzania.
作者信息
Mboowa Gerald, Kidenya Benson R, Sserwadda Ivan, Kanyerezi Stephen, Akaro Inyasi Lawrence, Mkinze Baraka, Seni Jeremiah
机构信息
Department of Immunology and Molecular Biology, College of Health Sciences, School of Biomedical Sciences, Makerere University, Kampala, Uganda.
The African Center of Excellence in Bioinformatics and Data-Intensive Sciences, the Infectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
出版信息
Microbiol Resour Announc. 2025 Aug 14;14(8):e0036325. doi: 10.1128/mra.00363-25. Epub 2025 Jul 2.
We report draft genomes of three isolates from Tanzania. Genomes averaged 6.9 Mb with 51.49% GC content and 114× depth. ST167 carried multiple extended-spectrum β-lactamase, fluoroquinolone, and aminoglycoside resistance genes alongside virulence factors, highlighting the need for genomic surveillance of emerging multidrug-resistant lineages.
我们报告了来自坦桑尼亚的三株分离株的基因组草图。基因组平均大小为6.9 Mb，GC含量为51.49%，深度为114倍。ST167携带多个超广谱β-内酰胺酶、氟喹诺酮和氨基糖苷类耐药基因以及毒力因子，凸显了对新兴多重耐药谱系进行基因组监测的必要性。
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