Walsh C H, Malins J M
Br Med J. 1977 Jul 16;2(6080):177-9. doi: 10.1136/bmj.2.6080.177.
Seventy per cent of the patients aged 45 years or under and suffering from diabetic ketoacidosis who were seen in one diabetic clinic over five years were women. The association of menstruation with ketoacidosis was assessed over two and a half years, and it was found that menstruation was associated with ketoacidosis more often than would be expected by chance (P less than 0-01). Two hundred women were interviewed and 76 observed that menstruation changed their diabetic control. Fifty-three found that control deteriorated and hyperglycaemia occurred, while 23 found that control improved and hypoglycaemia was a common problem. Menstruation appears to be an important factor in influencing control of diabetes. The mechanism of the changes observed has not yet been determined, but it seems to be a subject worthy of further investigation.
在一家糖尿病诊所五年间接诊的45岁及以下患有糖尿病酮症酸中毒的患者中，70%为女性。在两年半的时间里对月经与酮症酸中毒的关联进行了评估，发现月经与酮症酸中毒的关联比偶然预期的更为频繁（P小于0.01）。对200名女性进行了访谈，其中76人观察到月经改变了她们的糖尿病控制情况。53人发现控制情况恶化并出现高血糖，而23人发现控制情况改善但低血糖是常见问题。月经似乎是影响糖尿病控制的一个重要因素。所观察到的变化机制尚未确定，但这似乎是一个值得进一步研究的课题。
