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复杂遗传系统中的选择。VI. 具有部分自交的双基因座选择模型的平衡性质。

Selection in complex genetic systems. VI. Equilibrium properties of two locus selection models with partial selfing.

作者信息

Holsinger K E, Feldman M W

出版信息

Theor Popul Biol. 1985 Aug;28(1):117-32. doi: 10.1016/0040-5809(85)90024-3.

DOI:10.1016/0040-5809(85)90024-3
PMID:4060083
Abstract

The results of a combined analytical and numerical study of two locus selection models with partial selfing indicate that several commonly held opinions about the effects of partial self-fertilization do not hold in general. For example, the heterozygosity of a population may actually increase as the selfing rate is increased. Similarly, selection strong enough to guarantee a two locus polymorphism with complete selfing does not necessarily guarantee a two locus polymorphism with intermediate amounts of self-fertilization. The results presented here and a brief review of previously existing results indicate that the predictions of population genetic models based on the assumption of random mating will not be greatly altered by a small amount of self-fertilization, unless the loci involved are tightly linked. On the other hand, the results presented indicate that a very small amount of outcrossing may lead to marked differences from the expectation based on complete self-fertilization.

摘要

一项对具有部分自交的两个基因座选择模型的综合分析和数值研究结果表明,一些关于部分自花受精影响的普遍观点通常并不成立。例如,随着自交率的增加,种群的杂合度实际上可能会增加。同样,足以保证完全自交时两个基因座多态性的选择并不一定能保证中等自花受精量时的两个基因座多态性。此处给出的结果以及对先前已有结果的简要回顾表明,基于随机交配假设的群体遗传模型的预测不会因少量自花受精而发生很大改变,除非所涉及的基因座紧密连锁。另一方面,给出的结果表明,极少量的异交可能导致与基于完全自花受精的预期有显著差异。

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