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定制远程患者管理以优化初级保健中的心血管风险管理:一项为大规模实施提供信息的混合方法实施研究。

Tailoring remote patient management to optimise cardiovascular risk management in primary care: a mixed-methods implementation study informing large-scale implementation.

作者信息

Rakers Margot, van Hattem Nicoline, Hiddink Eric, Peet Petra van, Vos Rimke, Chavannes Niels, Atsma Douwe, Bonten Tobias, van Os Hendrikus

机构信息

Department of Public Health and Primary Care, Leiden University Medical Center, 2333 ZA, Leiden, the Netherlands.

National eHealth Living Lab (NeLL), Leiden University Medical Center, Albinusdreef 2, ZA, Leiden, 2333, the Netherlands.

出版信息

BMC Prim Care. 2025 Jul 2;26(1):214. doi: 10.1186/s12875-025-02906-x.

Abstract

AIM

Remote patient management (RPM) effectively aids cardiovascular risk management, but its large-scale implementation remains challenging. Panel management may facilitate implementation by using comprehensive data to identify patients at risk of cardiovascular diseases and tailor interventions. This study evaluated the implementation strategies and clinical outcomes of a multi-component RPM intervention 'Connect@Heart'.

METHODS

We conducted a mixed-methods study over six months in four primary care practices in the Netherlands, evaluating two patient groups: (i) patients with a BMI < 25 received a blood pressure monitor alone (BP Box), and (ii) patients with a BMI > 25 or cardiovascular disease received a combination of a BP monitor, a scale, and an activity tracker (Lifestyle Box). Baseline and six-month follow-up assessments were performed using linear mixed-effects models, and implementation outcomes were evaluated using the RE-AIM framework.

RESULTS

Our approach achieved high enrolment, with 189 out of 200 initially interested patients (94%) participating. The intervention was associated with a significant reduction in BP levels within both groups (BP Box systolic BP from 139 ± 21 mmHg at baseline to 132 ± 18 mmHg at follow-up, p < 0.001 and Lifestyle Box 142 ± 16 mmHg to 131 ± 14 mmHg at follow-up, p < 0.001), especially for those with uncontrolled hypertension. After six months, 66% of patients performed measurements weekly. All participating practices continued using the intervention post-study.

CONCLUSION

This study demonstrates that proactively identifying patient panels at risk for CVD and tailoring multi-component RPM interventions to patient panels are promising implementation strategies for reaching favourable clinical outcomes at scale.

摘要

目的

远程患者管理(RPM)有效辅助心血管风险管理,但其大规模实施仍具挑战性。小组管理可通过利用综合数据识别心血管疾病风险患者并量身定制干预措施来促进实施。本研究评估了多组分RPM干预措施“心连心”(Connect@Heart)的实施策略和临床结果。

方法

我们在荷兰的四个初级保健机构进行了为期六个月的混合方法研究,评估了两个患者组:(i)体重指数(BMI)<25的患者仅接受血压监测仪(血压盒),(ii)BMI>25或患有心血管疾病的患者接受血压监测仪、体重秤和活动追踪器的组合(生活方式盒)。使用线性混合效应模型进行基线和六个月随访评估,并使用RE-AIM框架评估实施结果。

结果

我们的方法实现了高参与率,最初感兴趣的200名患者中有189名(94%)参与。两组患者的血压水平均显著降低(血压盒组收缩压从基线时的139±21 mmHg降至随访时的132±18 mmHg,p<0.001;生活方式盒组从142±16 mmHg降至随访时的131±14 mmHg,p<0.001),尤其是对于那些高血压未得到控制的患者。六个月后,66%的患者每周进行测量。所有参与的机构在研究结束后继续使用该干预措施。

结论

本研究表明,主动识别有心血管疾病风险的患者小组并为患者小组量身定制多组分RPM干预措施是有望实现大规模良好临床结果的实施策略。

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