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两种不同数字化构建技术的下颌种植覆盖义齿对种植体周围骨吸收和后牙嵴吸收的影响:一项为期3年的前瞻性随机临床试验

Effect of two different digital construction techniques of mandibular implant-assisted overdentures on peri-implant bone loss and posterior ridge resorption: a 3-year prospective randomized clinical trial.

作者信息

El Khamisy Nermeen El Sayed, Emera Radwa M K, Elmanci Thuraya Maher, Aboelez Marwa Ahmed

机构信息

Faculty of Dentistry, Mansoura University, Mansoura, Egypt.

出版信息

BMC Oral Health. 2025 Jul 2;25(1):1040. doi: 10.1186/s12903-025-06425-0.

DOI:10.1186/s12903-025-06425-0
PMID:40604700
Abstract

OBJECTIVES

Traditional complete denture (CD) design and fabrication techniques need several clinical and laboratory steps. To improve the qualities of denture base material and get rid of all the problems that come with the conventional fabrication process, novel production methods were approved. In the field of denture manufacture, new materials and computer-aided technology have been explored as potential solutions. So, this study aimed to investigate the effect of two different digital construction techniques of implant-assisted overdentures on peri-implant and posterior mandibular bone resorptions by CBCT.

MATERIALS AND METHODS

Twenty patients who received mandibular overdenture constructed by different construction techniques were classified equally and randomly into two groups (n = 10 per group): Group M: received milled mandibular overdenture opposed by maxillary complete denture. Group P: received 3D-printed mandibular overdenture opposed by maxillary complete denture. Peri-implant bone loss and posterior ridge resorption were assessed at baseline (T0), at 1 year(T1), and 3 years(T3) by superimposition of pre and post-treatment CBCT.The Shapiro-Wilk test was used to access data that was not normally distributed. Two distinct groups were compared using the Mann-Whitney test. The Wilcoxon signed-rank test was used to compare paired groups.

RESULTS

Regarding vertical bone loss(VBL), Group P recorded higher VBL in comparison to Group M, where the mean was 0.57 ± 0.13, and 0.52 ± 0.12respectively, at T1 and 0.66 ± 0.11, 0.60 ± 0.12 at T3. There was a statistically significant difference at different times of evaluation within the groups where (P < 0.001). Regarding posterior ridge resorption(PRR), Group P recorded higher PRR in comparison to Group M, where the mean was 381 ± 18.5, 333 ± 17.2 respectively at T1and 533 ± 24.9, 478.5 ± 12.3 at T3. There was a statistically significant difference at different times of evaluation within the groups where (P = 0.005).

CONCLUSION

Regarding the preservation of peri-implant alveolar bone and posterior ridge bone, milled implant-assisted complete overdentures may have more favorable clinical outcomes compared to 3D printed implant overdentures in the digitally constructed mandibular overdenture bases retained by two implants.

CLINICAL RELEVANCE

Both milled and 3D printed implant overdenture impression techniques can be used for the construction of CAD/CAM-implant retained overdenture base. However, in regarding the peri-implant alveolar bone and posterior ridge bone resorption, milled implant-assisted complete overdentures may have more favorable clinical outcomes compared to 3D printed implant overdentures retained by two implants.

CLINICAL TRIAL REGISTRY NUMBER

(No.-NCT06720389) (03/12/2024).

摘要

目的

传统全口义齿(CD)的设计和制作技术需要多个临床和实验室步骤。为了提高义齿基托材料的质量并消除传统制作工艺带来的所有问题,新型制作方法得到了认可。在义齿制造领域,新材料和计算机辅助技术已被探索作为潜在解决方案。因此,本研究旨在通过CBCT研究两种不同的种植体支持覆盖义齿数字构建技术对种植体周围和下颌后部骨吸收的影响。

材料与方法

20例接受不同构建技术制作下颌覆盖义齿的患者被平均随机分为两组(每组n = 10):M组:接受由上颌全口义齿对合的铣削下颌覆盖义齿。P组:接受由上颌全口义齿对合的3D打印下颌覆盖义齿。通过治疗前后CBCT叠加,在基线(T0)、1年(T1)和3年(T3)评估种植体周围骨丢失和后牙嵴吸收。使用Shapiro-Wilk检验来分析非正态分布的数据。使用Mann-Whitney检验比较两个不同组。使用Wilcoxon符号秩检验比较配对组。

结果

关于垂直骨丢失(VBL),P组记录的VBL高于M组,T1时平均值分别为0.57±0.13和0.52±0.12,T3时为0.66±0.11和0.60±0.12。在组内不同评估时间存在统计学显著差异(P < 0.001)。关于后牙嵴吸收(PRR),P组记录的PRR高于M组,T1时平均值分别为381±18.5和333±17.2,T3时为533±24.9和478.5±12.3。在组内不同评估时间存在统计学显著差异(P = 0.005)。

结论

关于种植体周围牙槽骨和后牙嵴骨的保存,在由两颗种植体固位的数字构建下颌覆盖义齿基托中,铣削的种植体支持全覆盖义齿可能比3D打印的种植体覆盖义齿具有更有利的临床结果。

临床相关性

铣削和3D打印种植体覆盖义齿印模技术均可用于CAD/CAM种植体固位覆盖义齿基托的构建。然而,关于种植体周围牙槽骨和后牙嵴骨吸收,铣削种植体支持全覆盖义齿可能比两颗种植体固位的3D打印种植体覆盖义齿具有更有利的临床结果。

临床试验注册号

(编号 - NCT06720389)(2024年12月3日)。

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Effect of two different digital construction techniques of mandibular implant-assisted overdentures on peri-implant bone loss and posterior ridge resorption: a 3-year prospective randomized clinical trial.两种不同数字化构建技术的下颌种植覆盖义齿对种植体周围骨吸收和后牙嵴吸收的影响:一项为期3年的前瞻性随机临床试验
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本文引用的文献

1
Are There Clinical Differences Between 3D-Printed and Milled Complete Dentures? A Systematic Review and Meta-analysis.3D打印全口义齿和铣削全口义齿之间存在临床差异吗?一项系统评价和荟萃分析。
Int Dent J. 2025 Apr;75(2):464-473. doi: 10.1016/j.identj.2024.11.007. Epub 2024 Dec 12.
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Evaluation of the methods for determining accuracy of fit and precision of RPD framework in Digital (3D printed, milled) and conventional RPDs - a systematic review.数字(3D打印、铣削)和传统可摘局部义齿(RPD)中RPD框架适合度准确性和精度测定方法的评估——一项系统评价
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A Comparison of Denture Base Retention and Adaptation Between CAD/CAM and Conventional Fabrication Techniques.
CAD/CAM 和传统制作技术在义齿基托保留和适应性方面的比较。
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Evaluation of physicomechanical properties of milled versus 3D-printed denture base resins: A comparative in vitro study.铣削与 3D 打印义齿基托树脂的理化性能评估:一项体外比较研究。
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Efficacy of low-dose cone beam computed tomography and metal artifact reduction tool for assessment of peri-implant bone defects: an in vitro study.低剂量锥形束 CT 和金属伪影降低工具评估种植体周围骨缺损的疗效:一项体外研究。
BMC Oral Health. 2022 Dec 17;22(1):615. doi: 10.1186/s12903-022-02663-8.
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Fit and retention of complete denture bases: Part II - conventional impressions versus digital scans: A clinical controlled crossover study.全口义齿基托的贴合度与固位:第二部分 - 传统印模与数字扫描:一项临床对照交叉研究。
J Prosthet Dent. 2024 Apr;131(4):618-625. doi: 10.1016/j.prosdent.2022.07.004. Epub 2022 Aug 30.
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Tissue Surface Adaptation and Clinical Performance of CAD-CAM Milled versus Conventional Implant-Assisted Mandibular Overdenture.计算机辅助设计与制造(CAD-CAM)铣削式与传统种植体支持下颌覆盖义齿的组织表面适应性及临床性能
Int J Dent. 2022 Jun 16;2022:8220233. doi: 10.1155/2022/8220233. eCollection 2022.
8
Implications of considering peri-implant bone loss a disease, a narrative review.将种植体周围骨丧失视为一种疾病的影响:叙述性综述。
Clin Implant Dent Relat Res. 2022 Aug;24(4):532-543. doi: 10.1111/cid.13102. Epub 2022 May 31.
9
Comparison of Dimensional Changes Between CAD-CAM Milled Complete Denture Bases and 3D Printed Complete Denture Bases: An In Vitro Study.计算机辅助设计与制造(CAD-CAM)铣削全口义齿基托和3D打印全口义齿基托尺寸变化的比较:一项体外研究。
J Prosthodont. 2023 Apr;32(S1):11-19. doi: 10.1111/jopr.13538. Epub 2022 May 18.
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Angled ball and locator attachments for immediate loaded inclined implants used to retain maxillary overdentures: A cross over study of patient satisfaction and oral health related quality of life.用于保留上颌覆盖义齿的即刻加载倾斜种植体的角度球和定位器附件:患者满意度和口腔健康相关生活质量的交叉研究。
Clin Implant Dent Relat Res. 2022 Jun;24(3):391-400. doi: 10.1111/cid.13089. Epub 2022 May 3.