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鹰综合征作为一种迟发性血管并发症:高颈段狭窄支架置入术后颈动脉支架变形

Eagle Syndrome as a Delayed Vascular Complication: Carotid Stent Deformation After Stenting for High Cervical Stenosis.

作者信息

Kumono Takahiro, Tanaka Tatsuya, Naito Tomoyuki, Matsuno Akira

机构信息

Department of Neurosurgery, International University of Health and Welfare, Narita Hospital, Narita, JPN.

出版信息

Cureus. 2025 Jun 1;17(6):e85205. doi: 10.7759/cureus.85205. eCollection 2025 Jun.

DOI:10.7759/cureus.85205
PMID:40605897
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12213308/
Abstract

Eagle syndrome, caused by elongation of the styloid process or calcification of the stylohyoid ligament, can present with a variety of symptoms. The vascular variant, stylocarotid syndrome, involves mechanical compression of the internal carotid artery (ICA) and may lead to cerebrovascular complications such as dissection, transient ischemic attacks, or ischemic stroke. While carotid artery stenting (CAS) is widely used for carotid stenosis, mechanical complications related to surrounding bony structures remain rare. We report a case of a 75-year-old woman who underwent CAS for high cervical ICA stenosis. Although the procedure was initially successful, the patient later developed recurrent ischemic stroke. Imaging revealed in-stent restenosis caused by deformation of the carotid stent, which was in close proximity to an elongated styloid process (44 mm). The patient underwent percutaneous transluminal angioplasty, followed by transcervical styloidectomy. After the final intervention, the patient remained free of restenosis or stroke recurrence during a one-year follow-up period. This case highlights the importance of evaluating bony anatomical structures in patients undergoing CAS, particularly for high cervical lesions. An elongated styloid process may cause delayed mechanical stent deformation and restenosis. Early recognition and consideration of styloidectomy may help prevent complications and improve long-term outcomes in vascular Eagle syndrome.

摘要

鹰综合征由茎突过长或茎突舌骨韧带钙化引起,可表现出多种症状。血管变异型,即茎突颈动脉综合征,涉及颈内动脉(ICA)的机械性压迫,并可能导致诸如夹层、短暂性脑缺血发作或缺血性中风等脑血管并发症。虽然颈动脉支架置入术(CAS)广泛用于治疗颈动脉狭窄,但与周围骨性结构相关的机械并发症仍然少见。我们报告一例75岁女性患者,因高位颈段ICA狭窄接受了CAS治疗。尽管手术最初成功,但患者后来发生了复发性缺血性中风。影像学检查显示,颈动脉支架变形导致支架内再狭窄,该支架紧邻一根过长的茎突(44毫米)。患者接受了经皮腔内血管成形术,随后进行了经颈茎突切除术。在最后一次干预后,患者在一年的随访期内未再出现再狭窄或中风复发。该病例强调了在接受CAS治疗的患者中评估骨性解剖结构的重要性,特别是对于高位颈段病变。过长的茎突可能导致支架延迟机械变形和再狭窄。早期识别并考虑茎突切除术可能有助于预防并发症并改善血管性鹰综合征的长期预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8183/12213308/16c8ae0da49a/cureus-0017-00000085205-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8183/12213308/198f558d33f8/cureus-0017-00000085205-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8183/12213308/eda8a6fb5710/cureus-0017-00000085205-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8183/12213308/2de7be691e9a/cureus-0017-00000085205-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8183/12213308/16c8ae0da49a/cureus-0017-00000085205-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8183/12213308/198f558d33f8/cureus-0017-00000085205-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8183/12213308/eda8a6fb5710/cureus-0017-00000085205-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8183/12213308/2de7be691e9a/cureus-0017-00000085205-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8183/12213308/16c8ae0da49a/cureus-0017-00000085205-i04.jpg

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本文引用的文献

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Eagle Syndrome: Pathophysiology, Differential Diagnosis and Treatment Options.鹰嘴综合征:病理生理学、鉴别诊断及治疗选择
Health Psychol Res. 2023 Feb 21;10(5):67851. doi: 10.52965/001c.67851. eCollection 2022.
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Vascular variant of Eagle syndrome: a review.鹰综合征的血管变异型:综述
Front Neurol. 2024 Oct 8;15:1463275. doi: 10.3389/fneur.2024.1463275. eCollection 2024.
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Surgical management of stylocarotid Eagle syndrome in a patient with bilateral internal carotid artery dissection: illustrative case.双侧颈内动脉夹层患者茎突颈动脉型鹰综合征的外科治疗:病例说明
J Neurosurg Case Lessons. 2024 Jan 29;7(5). doi: 10.3171/CASE23682.
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Fracture of a Flow Diverter in the Cervical Internal Carotid Artery Due to Eagle Syndrome.因鹰综合征导致的颈内动脉血流分流器骨折
Neurointervention. 2023 Mar;18(1):72-75. doi: 10.5469/neuroint.2022.00409. Epub 2023 Jan 10.
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Eagle syndrome causing severe stenosis of the internal carotid artery.鹰综合征导致颈内动脉严重狭窄。
CMAJ. 2021 Jul 19;193(28):E1091. doi: 10.1503/cmaj.202803.
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A Staged Therapy for Internal Carotid Artery Dissection Caused by Vascular Eagle Syndrome.血管型鹰钩鼻综合征导致的颈内动脉夹层的分期治疗。
World Neurosurg. 2019 Sep;129:133-139. doi: 10.1016/j.wneu.2019.05.208. Epub 2019 May 30.
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NMC Case Rep J. 2014 Dec 6;2(1):21-25. doi: 10.2176/nmccrj.2014-0179. eCollection 2015 Jan.
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Interv Neuroradiol. 2017 Aug;23(4):433-436. doi: 10.1177/1591019917706050. Epub 2017 May 22.
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