Weible Alan H, Wang Xiaoguang
William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio 43210, United States.
Sustainability Institute, The Ohio State University, Columbus, Ohio 43210, United States.
ACS Cent Sci. 2025 Jun 6;11(6):828-830. doi: 10.1021/acscentsci.5c00983. eCollection 2025 Jun 25.
The divergence of conformational ensembles of hIAPP in response to different types of mutations and PTMs has been decoded by leveraging the scanning tunneling microscopy-based probability interpretation technique.
通过利用基于扫描隧道显微镜的概率解释技术，已解码出人胰岛淀粉样多肽（hIAPP）构象集合对不同类型突变和翻译后修饰（PTM）的响应差异。
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