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骨内通路后发生静脉空气栓塞:一例报告及超声心动图表现

Venous Air Embolism Following Intraosseous Access: A Case Report and Echocardiographic Findings.

作者信息

Amiot Félix, Ramakers Michel, Fleury Dan, Malherbe Jolan

机构信息

Department of Emergency Medicine, SAMU 50, Centre Hospitalier Mémorial France Etats-Unis, Saint-Lô, France.

Service de réanimation, Centre Hospitalier Mémorial France Etats-Unis, Saint-Lô, France.

出版信息

J Am Coll Emerg Physicians Open. 2025 Jun 16;6(4):100201. doi: 10.1016/j.acepjo.2025.100201. eCollection 2025 Aug.

DOI:10.1016/j.acepjo.2025.100201
PMID:40606318
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12213290/
Abstract

Venous air embolism (VAE) is a rare but potentially life-threatening complication of intraosseous access. We report the case of a 57-year-old woman who presented to the emergency department following deliberate self-poisoning and subsequently developed VAE associated with intraosseous access. Transthoracic echocardiography revealed acute cor pulmonale with air bullae migrating from the inferior vena cava to the right heart cavities and the pulmonary circulation, indicating massive VAE. Associated patent foramen ovale was diagnosed by transesophageal echocardiography, suggesting paradoxical embolism. This case highlights the importance of caution with intraosseous access, especially when using semirigid containers and pressure-infusion devices. Emergency and intensive-care physicians should be aware of the VAE risk associated with semirigid containers to promptly recognize and treat VAE events.

摘要

静脉空气栓塞(VAE)是骨内通路一种罕见但可能危及生命的并发症。我们报告了一例57岁女性的病例,该患者因蓄意自我中毒后就诊于急诊科,随后发生了与骨内通路相关的VAE。经胸超声心动图显示急性肺心病,气泡从下腔静脉迁移至右心腔和肺循环,提示大量VAE。经食管超声心动图诊断为伴有卵圆孔未闭,提示反常栓塞。该病例强调了骨内通路操作时谨慎的重要性,尤其是在使用半刚性容器和压力输注装置时。急诊和重症监护医生应意识到与半刚性容器相关的VAE风险,以便及时识别和治疗VAE事件。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1bb/12213290/e51efdbdb873/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1bb/12213290/e51efdbdb873/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1bb/12213290/e51efdbdb873/gr1.jpg

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本文引用的文献

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Point-Of-Care Ultrasound Diagnosis of Intravascular Air After Lower Extremity Intraosseous Access.
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Long-term outcome of iatrogenic gas embolism.医源性气体栓塞的长期转归。
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Cerebral arterial air embolism in a child after intraosseous infusion.儿童骨内输液后发生脑动脉空气栓塞。
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Diagnosis and treatment of vascular air embolism.血管空气栓塞的诊断与治疗。
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Iatrogenic cerebral air embolism: importance of an early hyperbaric oxygenation.医源性脑空气栓塞:早期高压氧疗的重要性。
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Volume of air in a lethal venous air embolism.致死性静脉空气栓塞中的空气量。
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Gas embolism.气体栓塞
N Engl J Med. 2000 Feb 17;342(7):476-82. doi: 10.1056/NEJM200002173420706.