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基于深度学习的旋转物体检测算法用于脊柱侧弯X线图像中Cobb角的自动测量

Deep learning-based rotational object detection algorithm for automatic Cobb angle measurement in X-ray images of scoliosis.

作者信息

Liu Yichong, Shi Zhiliang, Xiao Chaoyang, Gao Yanzheng, Ren Hao, Wang Xinyi

机构信息

School of Mechanical and Electrical Engineering, Wuhan University of Technology, Wuhan, China.

Department of Orthopedics, Henan Provincial People's Hospital, Zhengzhou, China.

出版信息

Quant Imaging Med Surg. 2025 Jun 6;15(6):5204-5217. doi: 10.21037/qims-24-2138. Epub 2025 May 25.

DOI:10.21037/qims-24-2138
PMID:40606352
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12209664/
Abstract

BACKGROUND

Scoliosis, characterized by an abnormal curvature of the spine, poses significant physiological challenges during adolescent growth and development. The Cobb angle measurement is regarded as the clinical gold standard for assessing the severity of scoliosis. The measurement of the Cobb angle has been extensively investigated through advanced neural network models; however, accurately measuring the Cobb angle remains challenging due to difficulties in detecting rotational vertebral objects. Therefore, this study aimed to develop an enhanced model that improves the detection of rotational vertebrae, thereby increasing the accuracy of Cobb angle measurements for more reliable scoliosis assessment.

METHODS

This study employed a redesigned YOLOv8-DSF model based on the YOLOv8n-oriented bounding box (OBB) framework, equipped with innovative modules to improve the detection of rotational objects. The method involves detecting vertebrae with rotational bounding boxes using the model and subsequently calculating the Cobb angle based on these detections. The model was tested and evaluated on a custom-built dataset that integrates private and publicly available data, all of which were enhanced through rigorous screening and augmentation processes.

RESULTS

The experimental findings demonstrated that the model achieved an mAP calculated with an Intersection over Union (IoU) threshold of 0.50 (mAP50) score of 0.626 and an mAP calculated with an IoU range of 0.50 to 95 (mAP50-95) score of 0.424, both exceeding the baseline by over 10%. In assessing Cobb angle accuracy, the model achieves a symmetric mean absolute percentage error (SMAPE) of 8.43 and an average mean absolute error (MAE) of 5.09 across the three Cobb angles. When tested on a public dataset for Cobb angle prediction accuracy, YOLOv8-DSF also demonstrated excellent performance.

CONCLUSIONS

Given that the model outperformed both the baseline and other existing methods in detecting rotational vertebral objects and calculating the Cobb angle, it contributes to more accurate scoliosis assessments. This advancement holds significant potential for clinical applications in scoliosis evaluation and management.

摘要

背景

脊柱侧弯的特征是脊柱出现异常弯曲,在青少年生长发育过程中带来重大生理挑战。Cobb角测量被视为评估脊柱侧弯严重程度的临床金标准。通过先进的神经网络模型对Cobb角测量进行了广泛研究;然而,由于难以检测旋转的椎体目标,准确测量Cobb角仍然具有挑战性。因此,本研究旨在开发一种增强模型,改进旋转椎体的检测,从而提高Cobb角测量的准确性,以进行更可靠的脊柱侧弯评估。

方法

本研究采用了基于面向YOLOv8n的边界框(OBB)框架重新设计的YOLOv8-DSF模型,配备了创新模块以改进旋转目标的检测。该方法包括使用模型通过旋转边界框检测椎体,随后基于这些检测结果计算Cobb角。该模型在一个定制数据集上进行测试和评估,该数据集整合了私有和公开可用数据,所有数据均通过严格的筛选和增强过程进行了强化。

结果

实验结果表明,该模型在交并比(IoU)阈值为0.50时计算的平均精度均值(mAP)得分为0.626,在IoU范围为0.50至0.95时计算的mAP得分为0.424,两者均比基线高出10%以上。在评估Cobb角准确性时,该模型在三个Cobb角上的对称平均绝对百分比误差(SMAPE)为8.43,平均平均绝对误差(MAE)为5.09。在用于Cobb角预测准确性的公共数据集上进行测试时,YOLOv8-DSF也表现出优异的性能。

结论

鉴于该模型在检测旋转椎体目标和计算Cobb角方面优于基线和其他现有方法,它有助于进行更准确的脊柱侧弯评估。这一进展在脊柱侧弯评估和管理的临床应用中具有巨大潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d05b/12209664/11c2cbdb4fa8/qims-15-06-5204-f7.jpg
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本文引用的文献

1
Deep learning algorithm for automatically measuring Cobb angle in patients with idiopathic scoliosis.深度学习算法自动测量特发性脊柱侧凸患者 Cobb 角。
Eur Spine J. 2024 Nov;33(11):4155-4163. doi: 10.1007/s00586-023-08024-5. Epub 2024 Feb 17.
2
AI-based automated detection and stability analysis of traumatic vertebral body fractures on computed tomography.基于人工智能的计算机断层扫描对创伤性椎体骨折的自动检测与稳定性分析
Eur J Radiol. 2024 Apr;173:111364. doi: 10.1016/j.ejrad.2024.111364. Epub 2024 Feb 13.
3
Probabilistic Intersection-Over-Union for Training and Evaluation of Oriented Object Detectors.
用于定向目标检测器训练和评估的概率交并比
IEEE Trans Image Process. 2024;33:671-681. doi: 10.1109/TIP.2023.3348697. Epub 2024 Jan 12.
4
The life and legacy of John Robert Cobb: the man behind the angle.约翰·罗伯特·科布的生平与遗产:幕后的角度大师。
J Neurosurg Spine. 2023 Sep 8;39(6):839-846. doi: 10.3171/2023.7.SPINE23146. Print 2023 Dec 1.
5
Accurate automated Cobb angles estimation using multi-view extrapolation net.使用多视图外推网络进行准确的自动 Cobb 角估计。
Med Image Anal. 2019 Dec;58:101542. doi: 10.1016/j.media.2019.101542. Epub 2019 Aug 9.
6
Patients with adolescent idiopathic scoliosis perceive positive improvements regardless of change in the Cobb angle - Results from a randomized controlled trial comparing a 6-month Schroth intervention added to standard care and standard care alone. SOSORT 2018 Award winner.青少年特发性脊柱侧凸患者无论 Cobb 角的变化如何,都能感知到积极的改善 - 来自比较施罗斯干预加标准护理与单纯标准护理 6 个月的随机对照试验的结果。2018 年 SRS 奖得主。
BMC Musculoskelet Disord. 2019 Jul 8;20(1):319. doi: 10.1186/s12891-019-2695-9.
7
Cobb Angle Measurement of Spine from X-Ray Images Using Convolutional Neural Network.使用卷积神经网络从X射线图像测量脊柱的Cobb角
Comput Math Methods Med. 2019 Feb 19;2019:6357171. doi: 10.1155/2019/6357171. eCollection 2019.
8
Comparison of two- and three-dimensional measurement of the Cobb angle in scoliosis.脊柱侧弯中Cobb角的二维和三维测量比较。
Int Orthop. 2017 May;41(5):957-962. doi: 10.1007/s00264-016-3359-0. Epub 2016 Dec 5.
9
Reliability assessment of Cobb angle measurements using manual and digital methods. Cobb 角测量的手动和数字方法的可靠性评估。
Spine J. 2010 Sep;10(9):769-74. doi: 10.1016/j.spinee.2010.02.020. Epub 2010 Apr 1.
10
Reliability analysis for manual adolescent idiopathic scoliosis measurements.青少年特发性脊柱侧弯手动测量的可靠性分析。
Spine (Phila Pa 1976). 2005 Feb 15;30(4):444-54. doi: 10.1097/01.brs.0000153702.99342.9c.