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艾滋病毒感染者对带状疱疹疫苗的知晓率和可接受性

Awareness and acceptability of herpes zoster vaccination in people living with HIV.

作者信息

Motet Christian, Libois Agnès, Martin Charlotte, Dauby Nicolas

机构信息

Department of Infectious Diseases, CHU Saint-Pierre, Université Libre de Bruxelles (ULB), Brussels, Belgium.

School of Public Health, Université Libre de Bruxelles (ULB), Brussels, Belgium.

出版信息

Prev Med Rep. 2025 Jun 16;56:103143. doi: 10.1016/j.pmedr.2025.103143. eCollection 2025 Aug.

Abstract

OBJECTIVE

The recombinant herpes zoster vaccine is recommended for aging populations to prevent herpes zoster. We aimed to assess awareness of herpes zoster and acceptance of the herpes zoster vaccine acceptance among people living with HIV (PLWH).

METHODS

We conducted a written survey among PLWH attending an HIV outpatient clinic in Brussels from March 2022 to April 2023. Participation was voluntary. We collected epidemiological data, assessed knowledge of herpes zoster and opinion about herpes zoster vaccine and vaccination in general. We described the surveyed cohort and reported their attitudes toward vaccination. Herpes zoster vaccine acceptance and general vaccine acceptance were defined as two binary outcome variables. We performed binary logistic regression to identify factors associated with vaccine acceptance.

RESULTS

A total of 327 patients completed the questionnaire. While 64 % reported being aware of herpes zoster, only one third reported a link between herpes zoster and varicella infection. The majority (77.1 %) declared being in favour of overall vaccination. Willingness to be vaccinated (regardless of vaccine type) was the factor associated with herpes zoster vaccine acceptance. General vaccine acceptance was associated with the belief that vaccination is useful for preventing infectious diseases.

CONCLUSIONS

Knowledge and awareness about herpes zoster were low among PLWH surveyed. Herpes zoster vaccine acceptance was more related to general attitudes toward vaccination rather than specific knowledge about herpes zoster.

摘要

目的

重组带状疱疹疫苗被推荐用于老年人群以预防带状疱疹。我们旨在评估艾滋病毒感染者(PLWH)对带状疱疹的知晓情况以及对带状疱疹疫苗的接受程度。

方法

我们于2022年3月至2023年4月对在布鲁塞尔一家艾滋病毒门诊就诊的PLWH进行了书面调查。参与是自愿的。我们收集了流行病学数据,评估了对带状疱疹的知晓情况以及对带状疱疹疫苗和一般疫苗接种的看法。我们描述了被调查队列并报告了他们对疫苗接种的态度。带状疱疹疫苗接受度和一般疫苗接受度被定义为两个二元结局变量。我们进行二元逻辑回归以确定与疫苗接受度相关的因素。

结果

共有327名患者完成了问卷。虽然64%的人报告知晓带状疱疹,但只有三分之一的人报告了带状疱疹与水痘感染之间的联系。大多数人(77.1%)宣称赞成总体疫苗接种。愿意接种疫苗(无论疫苗类型)是与带状疱疹疫苗接受度相关的因素。一般疫苗接受度与认为疫苗接种有助于预防传染病的信念相关。

结论

在接受调查的PLWH中,对带状疱疹的知识和知晓度较低。带状疱疹疫苗接受度更多地与对疫苗接种的总体态度相关,而非与对带状疱疹的具体知识相关。

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Vaccines for preventing herpes zoster in older adults.用于预防老年人带状疱疹的疫苗。
Cochrane Database Syst Rev. 2023 Oct 2;10(10):CD008858. doi: 10.1002/14651858.CD008858.pub5.
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Vaccines for preventing herpes zoster in older adults.预防老年人带状疱疹的疫苗。
Cochrane Database Syst Rev. 2016 Mar 3;3(3):CD008858. doi: 10.1002/14651858.CD008858.pub3.
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Vaccines for preventing herpes zoster in older adults.用于预防老年人带状疱疹的疫苗。
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