Vallée Alexandre, Fourn Erwan, Majerholc Catherine, Touche Pauline, Zucman David
Department of Clinical Research and Innovation, Foch Hospital, 92150 Suresnes, France.
Department of Internal Medicine, Réseau Ville Hôpital Val de Seine, Foch Hospital, 92150 Suresnes, France.
Vaccines (Basel). 2021 Mar 24;9(4):302. doi: 10.3390/vaccines9040302.
People living with HIV are a high-risk population concerning the coronavirus 19 (COVID-19) infection, with a poorer prognosis. It is important to achieve high COVID-19 vaccination coverage rates in this group as soon as possible. This project used self-reporting to assess vaccine hesitancy and acceptance among people living with HIV towards the novel COVID-19 vaccine. Sixty-eight (28.7%) participants among the 237 declared their hesitancy to be vaccinated against COVID-19. Participants who expressed concerns about their health ( < 0.001), the requirement of mandatory COVID-19 vaccination ( = 0.017), and their chronic disease status ( = 0.026) were independently associated with the acceptance of vaccination. Conversely, participants presenting general vaccine refusal ( < 0.001), concerns about the serious side effects of COVID-19 vaccines ( < 0.001), and those already thinking having an immune status to COVID-19 ( = 0.008) were independently associated with COVID-19 vaccine hesitancy. Our results suggest that vaccine strategy would be more successful in France with a communication strategy emphasizing the collective benefits of herd immunity in the population living with HIV and reassuring patients with chronic diseases about the safety of the proposed vaccines.
艾滋病毒感染者是感染新型冠状病毒19（COVID-19）的高危人群，预后较差。尽快在该群体中实现高COVID-19疫苗接种覆盖率很重要。本项目采用自我报告的方式来评估艾滋病毒感染者对新型COVID-19疫苗的接种犹豫和接受情况。在237名参与者中，有68名（28.7%）表示对接种COVID-19疫苗犹豫不决。对自身健康表示担忧（<0.001）、COVID-19强制接种要求（=0.017）以及慢性病状况（=0.026）的参与者与疫苗接种接受度独立相关。相反，表现出普遍拒绝接种疫苗（<0.001）、对COVID-19疫苗严重副作用表示担忧（<0.001）以及那些已经认为自己对COVID-19有免疫状态的参与者（=0.008）与COVID-19疫苗接种犹豫独立相关。我们的结果表明，在法国，如果采用一种沟通策略，强调群体免疫对艾滋病毒感染者群体的集体益处，并向慢性病患者保证所提议疫苗的安全性，疫苗接种策略可能会更成功。
