Kato Taiga, Ishii Nobuaki, Serizawa Naotaka, Ogawa Rei
From the Department of Plastic Surgery, Nippon Medical Schoosl Chibahokusoh Hospital, Inzai, Chiba, Japan.
Department of Dermatology, Nippon Medical School Chibahokusoh Hospital, Inzai, Chiba, Japan.
Plast Reconstr Surg Glob Open. 2025 Jul 1;13(7):e6932. doi: 10.1097/GOX.0000000000006932. eCollection 2025 Jul.
Diffuse plexiform neurofibroma (DPN) typically grows progressively. It can lead to disfigurement and functional impairment and carries a risk of life-threatening intratumoral hemorrhage. Here, an 85-year-old woman presented with a massive 23-cm-diameter DPN in the buttock area that began hemorrhaging after a fall. It was immediately treated with transcatheter arterial embolization, but 18 days later, the hematoma developed a methicillin-resistant (MRSA) infection. Consequently, after 5 days of anti-MRSA antibiotics, the DPN was entirely resected, and the large skin defect was covered with the hatchet-type lumbosacral flap. Intraoperative bleeding was only 200 mL. Anti-MRSA antibiotics were continued for 2 days. A seroma developed under the skin flap on postoperative day 21. It was readily treated with puncture drainage. Then, it resolved by postoperative day 39 after several single punctures performed every few days over the next 18 days. Flap necrosis was not observed. The patient was discharged 45 days after surgery. No recurrence was observed 2.5 years later. Thus, massive infected DPNs in the buttocks can be completely resected, and the resulting large defect successfully covered with the hatchet-type lumbosacral flap.
弥漫性丛状神经纤维瘤(DPN)通常呈进行性生长。它可导致毁容和功能障碍,并伴有危及生命的肿瘤内出血风险。在此,一名85岁女性患者臀部出现一个直径达23厘米的巨大DPN,跌倒后开始出血。立即对其进行了经导管动脉栓塞治疗,但18天后,血肿发生了耐甲氧西林金黄色葡萄球菌(MRSA)感染。因此,在使用抗MRSA抗生素治疗5天后,将DPN完全切除,并用斧型腰骶皮瓣覆盖大面积皮肤缺损。术中出血仅200毫升。继续使用抗MRSA抗生素2天。术后第21天皮瓣下出现血清肿。通过穿刺引流很容易进行了治疗。然后,在接下来的18天里每隔几天进行几次单次穿刺,术后第39天时血清肿消退。未观察到皮瓣坏死。患者术后45天出院。2.5年后未观察到复发。因此,臀部巨大感染性DPN可完全切除,由此产生的大缺损可成功地用斧型腰骶皮瓣覆盖。