Frolova I A, Samsonov M A, Paramonova E G, Meshcheriakova V A, Volkova I S
Vopr Pitan. 1985 Jul-Aug(4):7-10.
Examination of patients with chronic coronary heart disease who suffered myocardial infarction has shown that most of them had a high blood serum content of magnesium. The magnesium content was lowered in 25% of the examined and was maximal in serum of the patients under 40 years. A positive correlation of the magnesium content to the serum content of beta-cholesterol and a negative one to the content of pre-beta-cholesterol and triglycerides were noted. After dietetic management a tendency was observed toward a 24% decrease in the magnesium content in obese patients and a 20% decrease in patients with normal body weight. Both groups demonstrated a reduction (but within normal) in the high magnesium content and a moderate elevation of the initially lowered content. The measurement of the magnesium content in blood serum cannot be regarded as an informative enough test for revealing the role of magnesium in the pathogenesis of coronary heart disease.
对患有心肌梗死的慢性冠心病患者的检查表明,他们中的大多数人血清镁含量较高。25%的受检者镁含量降低,40岁以下患者的血清镁含量最高。发现镁含量与β-胆固醇的血清含量呈正相关,与前β-胆固醇和甘油三酯的含量呈负相关。经过饮食管理后,观察到肥胖患者的镁含量有降低24%的趋势,体重正常的患者降低20%。两组患者的高镁含量均有所降低(但仍在正常范围内),最初降低的含量有适度升高。血清镁含量的测定不能被视为揭示镁在冠心病发病机制中作用的足够有信息量的检测方法。