Meshcheriakova V A, Samsonov M A, Paramonova E G, Karabasova M A, Plotnikova O A
Vopr Pitan. 1985 Nov-Dec(6):3-8.
The effects of two isocaloric antiatherosclerotic diets (containing 120 g protein) differing in the amino acid composition of protein sources introduced were studied and compared in patients with coronary heart disease. Conventional protein sources were used in the first diet, whereas in the second diet, 15% of protein (by weight) was replaced by soybean protein isolate. A study was also made of the effect of dietetic management on lipid metabolism in blood serum. Hemocoagulation, capillary permeability, the kallikrein-kinin system, and immune responsiveness. An increase in the hypolipidemic effect of the diet was noted together with a decrease in the activity of the kallikrein-kinin system, capillary permeability, and body autosensitization upon introduction into the diet of soybean protein isolate. The increase of the protein quota as well as that attained by means of introducing in the diet of soybean protein isolate reduces the therapeutic effect of the diet on hemostasis.
对冠心病患者研究并比较了两种等热量抗动脉粥样硬化饮食（含120克蛋白质）的效果，这两种饮食中蛋白质来源的氨基酸组成不同。第一种饮食使用传统蛋白质来源，而在第二种饮食中，15%的蛋白质（按重量计）被大豆分离蛋白替代。还研究了饮食管理对血清脂质代谢、血液凝固、毛细血管通透性、激肽释放酶-激肽系统和免疫反应性的影响。在饮食中引入大豆分离蛋白后，注意到饮食的降血脂作用增强，同时激肽释放酶-激肽系统的活性、毛细血管通透性和身体自身致敏性降低。蛋白质配额的增加以及通过在饮食中引入大豆分离蛋白所达到的增加，会降低饮食对止血的治疗效果。
