Oe Makoto, Yamada Amika, Ifadah Erlin
Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 5-11-80, Kodatsuno, Kanazawa, Ishikawa Japan.
Division of Health Sciences, Graduate School of Medical Sciences, Kanazawa University, 5-11-80, Kodatsuno, Kanazawa, Ishikawa Japan.
Diabetol Int. 2025 Mar 27;16(3):520-527. doi: 10.1007/s13340-025-00814-0. eCollection 2025 Jul.
In patients with diabetes, autonomic neuropathy leads to reduced sweating, which can lead to dry skin, and if the condition worsens, these can progress from foot fissures to ulcers. Although foot skin care is important in patients with diabetes to prevent diabetes-related foot ulcers, there are no detailed guidelines that provide specific methodology for achieving this goal. This scoping review aimed to clarify what is known in the literature regarding foot skin care for dry skin for patients with diabetes and propose optimal foot skin care to help prevent diabetes-related foot ulcers.
Literature databases were searched and two independent researchers screened the articles according to the inclusion criteria and then extracted the data. To be included in the analysis, all reports had to be original articles/case studies, studies involving human subjects, and studies on foot skin care for dry skin for patients with diabetes.
Seven studies met the inclusion criteria. Findings showed that application of a moisturizer, especially a cream containing urea or a cream containing 15% glycerol, liquid, and 10% soft paraffin twice a day for at least two weeks, could help relieve dry feet.
Establishing optimal foot skin care for patients with diabetes may require further studies that examine the frequency and long-term effects of foot skin care interventions, with the ultimate outcome focused on the development of diabetes-related foot ulcers.
在糖尿病患者中，自主神经病变会导致出汗减少，进而引起皮肤干燥，若病情恶化，可能从足部皲裂发展为溃疡。尽管足部皮肤护理对糖尿病患者预防糖尿病相关足部溃疡很重要，但尚无详细指南提供实现这一目标的具体方法。本范围综述旨在阐明文献中关于糖尿病患者干性皮肤足部皮肤护理的已知内容，并提出最佳足部皮肤护理方法以帮助预防糖尿病相关足部溃疡。
检索文献数据库，两名独立研究人员根据纳入标准筛选文章，然后提取数据。要纳入分析，所有报告必须是原创文章/病例研究、涉及人类受试者的研究以及关于糖尿病患者干性皮肤足部皮肤护理的研究。
七项研究符合纳入标准。研究结果表明，每天两次涂抹保湿剂，尤其是含尿素的乳膏或含15%甘油、液体和10%软石蜡的乳膏，持续至少两周，有助于缓解足部干燥。
为糖尿病患者建立最佳足部皮肤护理可能需要进一步研究，以考察足部皮肤护理干预的频率和长期效果，最终目标是关注糖尿病相关足部溃疡的发生。
