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[大鼠实验性血吸虫病期间的免疫现象:特异性和非特异性因素的作用]

[Immune phenomena during experimental schistosomiasis in the rat: role of specific and non specific factors].

作者信息

Tribouley J, Tribouley-Duret J, Appriou M

出版信息

C R Acad Hebd Seances Acad Sci D. 1977 Mar 28;284(13):1239-41.

PMID:406073
Abstract

Partial immunity to Schistosoma mansoni in the rat can be obtained by injection of a bilharzian antigen together with Freund's complete adjuvant. The results are the same no matter what form of the parasite is used (infecting cercariae or adult). This immunity is the result of both specific and non-specific mechanisms, as is proved by the fact that a lesser but still quite clear degree of resistance to infestation can be obtained by injection of Freund's adjuvant alone.

摘要

通过注射曼氏血吸虫抗原与弗氏完全佐剂,可使大鼠获得对曼氏血吸虫的部分免疫力。无论使用何种形式的寄生虫(感染性尾蚴或成虫),结果都是相同的。这种免疫力是特异性和非特异性机制共同作用的结果,单独注射弗氏佐剂可获得较低但仍相当明显的抗侵染程度,这一事实证明了这一点。

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