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[大鼠实验性血吸虫病期间的免疫现象:特异性和非特异性因素的作用]

[Immune phenomena during experimental schistosomiasis in the rat: role of specific and non specific factors].

作者信息

Tribouley J, Tribouley-Duret J, Appriou M

出版信息

C R Acad Hebd Seances Acad Sci D. 1977 Mar 28;284(13):1239-41.

PMID:406073
Abstract

Partial immunity to Schistosoma mansoni in the rat can be obtained by injection of a bilharzian antigen together with Freund's complete adjuvant. The results are the same no matter what form of the parasite is used (infecting cercariae or adult). This immunity is the result of both specific and non-specific mechanisms, as is proved by the fact that a lesser but still quite clear degree of resistance to infestation can be obtained by injection of Freund's adjuvant alone.

摘要

通过注射曼氏血吸虫抗原与弗氏完全佐剂,可使大鼠获得对曼氏血吸虫的部分免疫力。无论使用何种形式的寄生虫(感染性尾蚴或成虫),结果都是相同的。这种免疫力是特异性和非特异性机制共同作用的结果,单独注射弗氏佐剂可获得较低但仍相当明显的抗侵染程度,这一事实证明了这一点。

相似文献

1
[Immune phenomena during experimental schistosomiasis in the rat: role of specific and non specific factors].[大鼠实验性血吸虫病期间的免疫现象:特异性和非特异性因素的作用]
C R Acad Hebd Seances Acad Sci D. 1977 Mar 28;284(13):1239-41.
2
Schistosoma mansoni: immediate hypersensitivity to adult antigens in the rat.曼氏血吸虫:大鼠对成虫抗原的速发型超敏反应。
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Acquired immunity to Schistosoma mansoni in the rat: measurement of immunity by the lung recovery technique.大鼠对曼氏血吸虫的获得性免疫:通过肺回收技术测定免疫力。
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Antibodies are involved in the protective immunity induced in mice by Schistosoma mansoni schistosomula tegument (Smteg) immunization.抗体参与了曼氏血吸虫尾蚴表皮(Smteg)免疫诱导的小鼠保护性免疫。
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Protection against Schistosoma mansoni achieved by immunization with sonicated parasite.通过用超声破碎的寄生虫进行免疫接种实现对曼氏血吸虫的防护。
Eur J Immunol. 1982 Apr;12(4):327-32. doi: 10.1002/eji.1830120413.
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Schistosoma mansoni ex vivo lung-stage larvae excretory-secretory antigens as vaccine candidates against schistosomiasis.曼氏血吸虫体外肺期幼虫排泄分泌抗原作为抗血吸虫病疫苗候选物
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Schistosoma mansoni: the attrition of a challenge infection in mice immunized with highly irradiated live cercariae.
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Comparison of the protective efficacy on mekongi schistosomiasis in mice induced by antigens derived from cercariae, schistosomulae and adult worms.尾蚴、童虫和成虫来源抗原对小鼠湄公血吸虫病的保护效果比较。
Asian Pac J Allergy Immunol. 1993 Jun;11(1):71-7.
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Induction of protective immunity against Schistosoma mansoni by a non living vaccine. I. Partial characterization of antigens recognized by antibodies from mice immunized with soluble schistosome extracts.非活性疫苗诱导针对曼氏血吸虫的保护性免疫。I. 用可溶性血吸虫提取物免疫的小鼠产生的抗体所识别抗原的部分特性分析
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Concomitant immunity and host antigens associated with schistosomiasis.与血吸虫病相关的伴随免疫和宿主抗原。
Int J Parasitol. 1971 May;1(1):43-9. doi: 10.1016/0020-7519(71)90045-2.